Living-related donor kidney transplantation:8 cases reports

LIU Hang; et al

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Living-related donor kidney transplantation:8 cases reports

更新时间：2024-01-17

- Living-related donor kidney transplantation:8 cases reports
- Journal of Chongqing Medical University Issue 9, Pages: 1145-1147(2008)
- 作者机构：
  
  重庆医科大学附属第一医院泌尿外科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R699.2
- Published：2008，
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[1]刘航,苟欣,梁思敏,吴小候.亲属活体肾移植(附8例报告)[J].重庆医科大学学报,2008(09):1145-1147.

LIU Hang, et al. Living-related donor kidney transplantation:8 cases reports. [J]. Journal of Chongqing Medical University (9):1145-1147(2008)
[1]刘航,苟欣,梁思敏,吴小候.亲属活体肾移植(附8例报告)[J].重庆医科大学学报,2008(09):1145-1147. DOI：

LIU Hang, et al. Living-related donor kidney transplantation:8 cases reports. [J]. Journal of Chongqing Medical University (9):1145-1147(2008) DOI：

摘要

目的:对2007～2008年8例终末期肾病患者实施亲属活体供肾肾移植的总结。方法:8例患者均为一代内血缘亲属供肾。术前均行（Human leacocfre antigen

HLA）配型、（Panel veactive antibady

PRA）及淋巴毒试验检查。通过ECT、CTA等检查进行供肾的筛选。经开放手术取肾

取左肾3例

右肾5例;受者均为第一次接受肾移植手术。术后以环孢素A（或他克莫司）、霉酚酸酯（或西罗莫司）及泼尼松三联抗排斥反应治疗。结果:供者术后10d左右出院

随访至今

肾功能均正常。受者术后28d内出院

出院时肾功能正常

随访2～14月

未见肾功能异常病例。结论:术前对供者的安全进行充分的评价及筛选

成熟的手术技术是手术成功的保证

术后坚持随访和合理应用免疫抑制剂是受者长期存活的关键。亲属活体肾移植组织配型好

手术成功率和长期存活率高

是治疗终末期肾病的有效手段。

Abstract

Objective:To introduce the experience on 8 cases living-related donor kidney transplantation(LD KT) in the past two years. Methods:8 patients underwent LDKT.The living donors(6 males and 2 females) received fully medical evaluation before operation. All cases were donated by blood relationship donors. CTA

ECT

HLA matching

PRA and CDC were done pre-operations. All t he donors underwent open nephrectomy

in which 5 cases donated right kidneys and 3 cases donated lef t kidneys. All the case underwent t he first renal transplantation. Triple-combined immuno suppressive protocols consisted of calcineurin inhibitors(CNI)

MMF and steroid. Results:All donors were discharged in ten days postoperation. Af ter followed up for 2 months to 14 months

all the donors kept normal kidney function without impairment of life quality. All the recipients were discharged in 28 days with normal kidney function

and keep the normal renal f unction till to now. Conclusion: Accurate pre-operation assessment of the donor’s safe and choose the donor kidney

good surgical technique are critical for the success. Optimal HLA matches and reasonable using of immunosuppressants can make the grafts survived long term. Living-rela ted donor kidney transplantation is a safe and effective reatment.

关键词

肾移植活体亲属供者

Keywords

renal transplantationRealated living donors

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Related Institution

Department of Anesthesia,College of Clinical Medicine,Chongqing Medical University

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Renal Transplantation Center,the First Affiliated Hospital,Chongqing Medical University

重庆医科大学附属第一医院肾移植中心

Department of Urology，The First Affiliated Hospital of Chongqing Medical University

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