JIAO Yang, et al. Effect of thyroid function on the status of anxiety and depression in patients with thyroid dysfunction. [J]. Journal of Chongqing Medical University (4):453-456(2008)
JIAO Yang, et al. Effect of thyroid function on the status of anxiety and depression in patients with thyroid dysfunction. [J]. Journal of Chongqing Medical University (4):453-456(2008)DOI:
Effect of thyroid function on the status of anxiety and depression in patients with thyroid dysfunction
Objective: To study the features of the emotional status of patients with thyroid dysfunction and analyze the relationship between levels of thyroid hormone and the emotion status.Methods: The levels of FT3
FT4 and TSH of 32 patients with hyperthyroidism
25 patients with hypothyroidism and 30 healthy persons(as normal control group) were measured.And Hamilton Anxiety Rating Scale(HAMA) and Hamilton Depression Rating Scale(HAMD) were used for evaluation of emotion status.The status of anxiety and depression in all groups were compared and the relationship between thyroid function and total scores of HAMA and HAMD were also analyzed.Results: There was statistical significant difference between the total scores of HAMA and HAMD in the hyperthyroidism group and hypothyroidism group and those of the normal control group(P< 0.01).FT4 levels are positively correlated with total scores of HAMD(P< 0.05) in the hyperthyroidism group.Conclusions: The Anxiety and depression symptoms were more severe in patients with hyperthyroidism and hypothyroidism than the healthy adults.There was correlation between the occurrence of depression and thyroid function in patients with hyperthyroidism.Thus improving thyroid function will help to relieve anxiety and depression emotion in the patients with thyroid disorders.