Objective:To report the pituitary sella MRI appearances

clinical symptoms and treatment of primary hypothyroidism in 7 cases

in order to improve the recognition of the pituitary sella MRI appearances

especially the MRI appearances of pituitary caused by the primary hypothyroidism

and to avoid misdiagnosis.Methods:The pituitary sella MRI appearances

clinical symptoms and clinical treatment in the primary hypothyroidism in those 7 cases were analyzed.Results:Features of the pituitary sella MRI appearances in those 7 cases:The pituitary increased in size

which appeared like the tumor in extreme.The MRI appearances of the superior carina were intermediate signal intensity

and the posterior lobe of the pituitary

with an obvious enhancement after Gd-DTPA administration

which was compressed by its anterior lobe

were high signal intensity;other MRI features included enlargement of the sella turcica

invasion of its adjacent bones and opticus nervus

and bad development of sphenoid sinus

etc.With T3

T4 decreasing and TSH markedly increasing that was measured by clinical laboratory examination

7 young children with hypothyroidism visited doctor due to a short stature

but their condition had been improved after an anti-hypothyroidism therapy for 1～ 3 months.The MRI features after treatment:The pituitary reduced largely in size.Conclusion:The primary hypothyroidism

with typical clinical symptoms

stimulates the pituitary that grows abnormally by the feedback regulation;it’s highly recommended to pay attention to clinical symptoms and laboratory examination so as to avoid misdiagnosis when the Cerebral MRI appearances mainly shows that the pituitary enlarges abnormally.