Clinical and laboratory analysis on 60 children with acute disseminated encephalomyelitis

LI Ming-chao; et al

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Clinical and laboratory analysis on 60 children with acute disseminated encephalomyelitis

更新时间：2024-01-17

- Clinical and laboratory analysis on 60 children with acute disseminated encephalomyelitis
- Journal of Chongqing Medical University Vol. 34, Issue 5, Pages: 637-639(2009)
- 作者机构：
  
  重庆医科大学附属儿童医院神经内科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R744.53
- Published：2009，
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[1]李明超,蒋莉.儿童播散性脑脊髓炎60例临床分析[J].重庆医科大学学报,2009,34(05):637-639.

LI Ming-chao, et al. Clinical and laboratory analysis on 60 children with acute disseminated encephalomyelitis. [J]. Journal of Chongqing Medical University 34(5):637-639(2009)
[1]李明超,蒋莉.儿童播散性脑脊髓炎60例临床分析[J].重庆医科大学学报,2009,34(05):637-639. DOI：

LI Ming-chao, et al. Clinical and laboratory analysis on 60 children with acute disseminated encephalomyelitis. [J]. Journal of Chongqing Medical University 34(5):637-639(2009) DOI：

摘要

目的:分析儿童急性播散性脑脊髓炎（Acute disseminated encephalomyelitis

ADEM）的临床和实验室特点

以提高对本病认识及早期诊断治疗。方法:对2005年1月至2007年1月重庆医科大学附属儿童医院60例ADEM患儿的临床表现、辅助检查及治疗预后进行分析。结果:60例中有前驱上呼吸道感染史者49例

疫苗接种史2例

无明显诱因9例。患儿均呈急性或亚急性起病;首发症状表现为活动障碍、意识障碍、惊厥及阵发性头痛头晕。临床主要表现为脑型30例

脑脊髓型25例

脊髓型5例。脑脊液48例异常

47例行MRI检查的患儿中43例异常

表现为脑皮质下或脊髓T1加权像呈低混合信号

T2加权像呈不均质信号或高信号。皮质激素、丙种球蛋白治疗ADEM有效。结论:儿童ADEM临床表现多样

呈多部位损害MRI表现具有一定的特征性

对本病诊断有一定的价值。

Abstract

Objective:To analyze the clinical and laboratory features of children with acute disseminated encephalomyelitis(ADEM)

in order to raise awareness of this disease and improve the early diagnosis and treatment.Methods:Clinical situation

auxiliary examination results

treatment and the prognosis of 60 children with ADEM admitted from January 2005 to January 2007 to Chongqing medical university Children’s hospital were analyzed.Results:In the 60 cases

there were 49 casea of history of upper respiratory tract infection

2 cases of history of vaccination

9 cases of no significant predispasition.The disease onset was acute or subacute;The first symptoms displayed disorder of the activities

conscious disturbance

convulsions and paroxysmal headache and dizziness.The main clinical manifestations showed 30 cases of brain-type

25 cases of brain-spinal cord

5 cases of spinal cord type.Cerebrospinal fluid of 48 cases was abnormal

MRI examination of 43 patients out of 47 patients

the cerebral cortex or spinal cord T1-weighted imaging showed low mixed signal

T2-weighted imaging was not homogeneous signal or high signal.Therapy with corticosteroids and immunoglobulin was effective for ADEM.Conclusion:The clinical features of children ADEM were diverse

multi-site damaged.MRI has certain characteristics and is valuable for the diagnosis of ADEM.

关键词

急性播散性脑脊髓炎儿童临床

Keywords

Acute disseminated encephalomyeliti(sADEM)childrenclinical

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Related Institution

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