Changes of serum and clinical implications of TNF-α,IL-10 and PAF in patients with acute lung injury

LI Xiao-liang; et al

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Changes of serum and clinical implications of TNF-α,IL-10 and PAF in patients with acute lung injury

更新时间：2024-01-17

- Changes of serum and clinical implications of TNF-α,IL-10 and PAF in patients with acute lung injury
- Journal of Chongqing Medical University Vol. 34, Issue 6, Pages: 772-774(2009)
- 作者机构：
  
  1. 重庆医科大学附属第一医院胸心外科
  2. 重庆市第二人民医院胸心外科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R563.8
- Published：2009，
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[1]李晓亮,向小勇,陈力,沈学远,洪斌.TNF-α、PAF、IL-10在急性肺损伤患者血清中的变化及意义[J].重庆医科大学学报,2009,34(06):772-774.

LI Xiao-liang, et al. Changes of serum and clinical implications of TNF-α,IL-10 and PAF in patients with acute lung injury. [J]. Journal of Chongqing Medical University 34(6):772-774(2009)
[1]李晓亮,向小勇,陈力,沈学远,洪斌.TNF-α、PAF、IL-10在急性肺损伤患者血清中的变化及意义[J].重庆医科大学学报,2009,34(06):772-774. DOI：

LI Xiao-liang, et al. Changes of serum and clinical implications of TNF-α,IL-10 and PAF in patients with acute lung injury. [J]. Journal of Chongqing Medical University 34(6):772-774(2009) DOI：

摘要

目的:探讨急性肺损伤患者血清中肿瘤坏死因子-α（Tumor necrosis factor-α

TNF-α）、血小板激活因子（Platelet activating factor

PAF）及白细胞介素-10（Interleukin-10

IL-10）的变化及意义。方法:采用ELISA方法检测临床上30例急性肺损伤患者血清中TNF-α、PAF、IL-10不同时间段的浓度变化并进行相关性分析。结果:肺损伤患者血清中TNF-α、PAF、IL-10的水平明显高于对照组。结论:血清TNF-α、PAF、IL-10在肺损伤中起着重要作用。提示这3种指标对肺损伤的诊断、治疗及预后有潜在的应用价值。

Abstract

Objective:To probe the changes of serum and clinical implications of TNF-α(tumor necrosis factors-α) of sera inflammatory cell factors and Interleukin-10(IL-10)

PAF in patients with acute lung injury.Methods:The dynamic variations of serum of TNF-α

IL-10

and PAF were tested through ELISA method in 30 strictly chosen patients with acute lung injury and 30 normal people

and relativity analysis was made.Results:There was significant increase levels of TNF-α

IL-10

and PAF in patients with acute lung injury.Conclusion:Serum TNF-α

PAF

IL-10 play an important role in lung injury.This prompts three kinds of indicators have potential application value in diagnosis

treatment and prognosis of lung injury.

关键词

肺损伤肿瘤坏死因子-α血小板激活因子白细胞介素-10

Keywords

Acute lung injurytumor necrosis factor-αPlatelet activating factorInter leukin-10

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