Clinical observation on 50 cases of acute cerebral infarction treated by fasudil hydrochloride

WANG Hai-chen; et al

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Clinical observation on 50 cases of acute cerebral infarction treated by fasudil hydrochloride

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- Clinical observation on 50 cases of acute cerebral infarction treated by fasudil hydrochloride
- Journal of Chongqing Medical University Issue S1, Pages: 89-90(2008)
- 作者机构：
  
  河南省浚县脑血管病医院神经科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R743.3
- Published：2008，
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[1]王海臣,姚新华,雷青翠.盐酸法舒地尔治疗急性脑梗死50例临床观察[J].重庆医科大学学报,2008(S1):89-90.

WANG Hai-chen, et al. Clinical observation on 50 cases of acute cerebral infarction treated by fasudil hydrochloride. [J]. Journal of Chongqing Medical University (S1):89-90(2008)
[1]王海臣,姚新华,雷青翠.盐酸法舒地尔治疗急性脑梗死50例临床观察[J].重庆医科大学学报,2008(S1):89-90. DOI：

WANG Hai-chen, et al. Clinical observation on 50 cases of acute cerebral infarction treated by fasudil hydrochloride. [J]. Journal of Chongqing Medical University (S1):89-90(2008) DOI：

摘要

目的:观察盐酸法舒地尔治疗急性脑梗死的临床疗效。方法:100例急性脑梗死患者随机分为治疗组和对照组各50例。两组同时给予肠溶阿司匹林片、盐酸川芎嗪注射剂、吡啦西坦氯化钠液及甘露醇液等;治疗组在对照组基础上加用盐酸法舒地尔30mg

溶于100ml5%葡萄糖或生理盐水中静脉滴注

每日2次

连用14d。结果:治疗组基本痊愈率、总有效率明显高于对照组（P<0.01）。治疗组神经功能缺损评分较治疗前显著降低（P<0.01）。结论:盐酸法舒地尔可有效改善脑梗死患者的临床预后

是治疗急性脑梗死安全有效的药物之一。

Abstract

Objective:To evaluate the clinical effects of fasudil hydrochloride on patients with acute cerebral infarction. Methods:100 cases of acute cerebral infarction patients were randomly divided into treatment group(n=50) and control group (n=50). All the cases were given enteric-coated tablets aspirin

ligustrazine hydrochloride injection

piracetam and sodium chlorideand injection and mannitol injection

and so on. Additionally

in the treatment group fasudil hydrochloride injection 30 mg

dissolved in 100 ml 5% glucose or saline were injected intravenously. Results:Basic recovery rate and total effective rate of treatment control were significantly higher(P<0.01) than control group. Neurologic impairment score of treatment group significantly decreased(P<0.01) than pretherapy. Conclusion: Fasudil hydrochloride can effectively improve the clinical prognosis of patients with acute cerebral infarction

and may become a safe and effective drug in treating acute cerebral infarction .

关键词

盐酸法舒地尔急性脑梗死

Keywords

Fasudil hydrochlorideacute cerebral infarction

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Related Institution

Department of Neurology，The First Affiliated Hospital of Chongqing Medical University

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Department of Radiology, Yan’an Hospital Affiliated to Kunming

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