Comparis on of sufentanil and fentanil during anesthesia in congenital funnel chest

TANG Wen; et al

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Comparis on of sufentanil and fentanil during anesthesia in congenital funnel chest

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- Comparis on of sufentanil and fentanil during anesthesia in congenital funnel chest
- Journal of Chongqing Medical University Vol. 34, Issue 5, Pages: 629-631(2009)
- 作者机构：
  
  重庆医科大学附属儿童医院麻醉科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R726.1
- Published：2009，
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[1]唐文,叶茂,舒仕瑜.舒芬太尼与芬太尼用于婴幼儿漏斗胸矫正术麻醉的比较[J].重庆医科大学学报,2009,34(05):629-631.

TANG Wen, et al. Comparis on of sufentanil and fentanil during anesthesia in congenital funnel chest. [J]. Journal of Chongqing Medical University 34(5):629-631(2009)
[1]唐文,叶茂,舒仕瑜.舒芬太尼与芬太尼用于婴幼儿漏斗胸矫正术麻醉的比较[J].重庆医科大学学报,2009,34(05):629-631. DOI：

TANG Wen, et al. Comparis on of sufentanil and fentanil during anesthesia in congenital funnel chest. [J]. Journal of Chongqing Medical University 34(5):629-631(2009) DOI：

摘要

目的:比较舒芬太尼和芬太尼在婴幼儿漏斗胸矫正术麻醉中对患儿血流动力学及术后苏醒质量的影响。方法:ASAⅠ～Ⅱ择期行先天性漏斗胸矫正术患儿40例

随机分为两组（n=20）:舒芬太尼组（SF组）和芬太尼组（F组）分别以舒芬太尼、芬太尼静脉诱导及麻醉维持

两组均复合丙泊酚、维库溴铵。观测记录麻醉诱导前（T0）、气管插管即刻（T1）、切皮时（T2）、剥离肋软骨时（T）3及手术结束时（T4）各时点心率（HR）、动脉收缩压（SBP）、动脉舒张压（DBP）、平均动脉压（MAP）

观察自主呼吸恢复时间、拔管时间与苏醒期躁动、术后呼吸抑制等不良反应。结果:与T0比较

F组T1～T3时SBP、DBP、MBP升高

HR增快（P<0.05）

SF组各时点差异无统计学意义;与SF组比较

F组T1～T3时SBP、DBP、MBP显著升高、HR明显增快（P<0.05）SF组自主呼吸恢复时间、拔管时间均短于F组（P<0.05）;与F组比较

SF组患儿苏醒期躁动等并发症少。结论:与芬太尼复合麻醉相比

舒芬太尼对血流动力学和应激反应影响小

是婴幼儿漏斗胸矫正术中比较理想的麻醉选择。

Abstract

Objective:To compare the effects of fentanil(F)or sufentanil(SF)for infant chondrosternoplasty on palinesthesia and hemodynamics.Methods:Forty patients were randomized divided into group F and group SF.Group SF received induction and intravenous injection with sufentanil

and group F received induction and continuous infusion with fentanil.HR

SBP

DBP and mean arterial pressure(MBP)were detected at different time points which including times before induction(T)0

immediately intubation(T1)

skin incision(T2)

peel rib cartilage(T)3and at the end of operation(T)4

meanwhile

anesthesia recovery condition and drug’s side effects were also recorded.Results:In group F

the values of SBP

DBP

MBP and HR have a significant increase at T1

T3 compared with baseline of To(P<0.05).The values of SBP

DBP

MBP and HR in group F at Tl

T3 were all have significance compared with those values in group SF at according time points(P<0.05).meanwhile the awaking time

The rates of spontaneous respiration

the extubation time in group SF were shorter than that in group F.Conclusion:Sufentanil with propofol could keep hemodynamic stable and minimum stress response

it might be an ideal drug combination in infant chondrosternoplasty.

关键词

舒芬太尼芬太尼麻醉先天性漏斗胸

Keywords

sufentanilfentanylanesthesiaCongenital funnel chest

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LI Da-zhen

Chen Yupei

Tian Zedan

Wan Mengning

Huang Zhenhua

Zhang Cheng

Xu Xiaoyan

Related Institution

Department of Anesthesia,the Children’s Hospital,Chongqing Medical University

Department of Anesthesiology,the Second Affiliated Hospital,Chongqing Medical University

Department of Anesthesiology,Chengdu Women & Children’s Central Hospital

Department of Anesthesiology,The First Hospital

重庆医科大学第一医院麻醉科

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