CT and MRI diagnosis of hepatic focal nodular hyperplasia

LI Yue-ming; et al.

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CT and MRI diagnosis of hepatic focal nodular hyperplasia

更新时间：2024-01-17

- CT and MRI diagnosis of hepatic focal nodular hyperplasia
- Journal of Chongqing Medical University Issue 10, Pages: 1171-1174(2008)
- 作者机构：
  
  福建医科大学附属第一医院影像科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R445;R575
- Published：2008，
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[1]李跃明,涂占海,李坚,吴凯明,李玉萍,曹代荣,李银官,杨小芳.肝脏局灶性结节性增生的CT及MRI诊断[J].重庆医科大学学报,2008(10):1171-1174.

LI Yue-ming, et al.. CT and MRI diagnosis of hepatic focal nodular hyperplasia. [J]. Journal of Chongqing Medical University (10):1171-1174(2008)
[1]李跃明,涂占海,李坚,吴凯明,李玉萍,曹代荣,李银官,杨小芳.肝脏局灶性结节性增生的CT及MRI诊断[J].重庆医科大学学报,2008(10):1171-1174. DOI：

LI Yue-ming, et al.. CT and MRI diagnosis of hepatic focal nodular hyperplasia. [J]. Journal of Chongqing Medical University (10):1171-1174(2008) DOI：

摘要

目的:探讨肝脏局灶性结节性增生（Focal nodular hyperplasia

FNH）的CT及MRI影像学特征。方法:回顾性分析19例经临床及病理证实为肝脏局灶性结节性增生的CT和MRI表现

CT检查16例

MRI检查10例

同时行CT和MRI检查7例。结合病理对其影像学征象进行综合分析。结果:19例FNH病灶均呈孤立结节或分叶状肿块

直径2～10cm

平均3.5cm。CT平扫呈等密度9例

略低密度7例

增强扫描动脉期除中心疤痕外病灶均明显强化;门脉期病灶呈稍高密度7例

等密度9例;平衡期及延迟期仍呈稍高密度5例

等密度11例;6个病灶的中央疤痕均呈延时强化。10例MRI平扫病灶呈长T1长T2信号

增强动脉期病灶均呈明显强化

门脉及平衡期呈稍高或等信号

4个病灶的中央疤痕延时强化。结论:典型的FNH影像学表现为动脉期明显均匀强化

门脉期及实质期呈高或等密度（信号）强化。延迟强化的裂隙样中央瘢痕有助于与肝细胞癌、肝腺瘤及肝血管瘤鉴别。

Abstract

Objective:To explore the characteristic findings of CT and MRI examinations in patients with focal nodular hyperplasia(FNH) of liver.Methods:All the CT and MRI findings of 19 cases with FNH confirmed by histopathology or clinicaldata were discussed retrospectively.16 patients examined with CT

10 cases with MRI scan

and 7 patients underwent both.All the imaging features were analyzed in combination with pathological findings.Results:All cases showed a solitary nodules or lobulated mass in the liver.The lesions were approximately 2 to 10 cm in diameter with an average diameter about 3.5cm.On plain CT scan

homogeneous area in 9 cases and slightly hypoattenuating zone were noted compared with the normal liver.The lesions showed heterogeneous or homogeneous hypodensity.On dynamic enhanced CT following intravenous contrast medium administration

all the lesions showed an early intensity and homogeneous enhancement except the central scars during arterial phase.7 cases displayed hyperattenuating and 9 cases demonstrated isoattenuation during the portal vein phase

5 cases showed hyperattenuating and 11 cases isoattenuattion during the equilibrium and delay phase.The central scars within 6 lesions showed delayed enhancement.On unenhanced MRI

10 cases showed hypointensity on T1WI and hyperintensity on T2WI.Dynamic contrast enhanced MRI with gadolinium DTPA showed enhancement pattern similar to that observed on contrast enhanced dynamic CT.All the lesions showed an early intensity and homogeneous enhancement during arterial phase

hyperintensity or hypointensity noted during the portal vein and equilibrium phase.Central scars within 4 lesions showed delayed enhancement.Conclusion:Typical cases with FNH show intense and homogeneous enhancement during arterial phase on dynamic enhanced CT and MRI following intravenous contrast medium administration.Hyperdensity or isodensity is displayed during portal vein phase and equilibrium phase.Crannied central scars with delayed enhancement are helpful to make differential diagnosis from hepatocellular carcinoma

hepatocelluar adenoma and hemangiomas.

关键词

肝脏局灶性结节性增生CT磁共振成像诊断

Keywords

Liver neoplasmFocal nodular hyperplasiaX-ray computed tomographymagnetic resonance imagingdiagnosis

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