Clinical signifi cance of pulmonary function tests in patients with acute pancreatitis

LAO You-yi

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Clinical signifi cance of pulmonary function tests in patients with acute pancreatitis

更新时间：2024-01-17

- Clinical signifi cance of pulmonary function tests in patients with acute pancreatitis
- Journal of Chongqing Medical University Vol. 34, Issue 9, Pages: 1280-1282(2009)
- 作者机构：
  
  广西省钦州市妇幼保健院消化内科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R576
- Published：2009，
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[1]劳有益.急性胰腺炎患者肺功能检测的临床意义[J].重庆医科大学学报,2009,34(09):1280-1282.

LAO You-yi. Clinical signifi cance of pulmonary function tests in patients with acute pancreatitis. [J]. Journal of Chongqing Medical University 34(9):1280-1282(2009)
[1]劳有益.急性胰腺炎患者肺功能检测的临床意义[J].重庆医科大学学报,2009,34(09):1280-1282. DOI：

LAO You-yi. Clinical signifi cance of pulmonary function tests in patients with acute pancreatitis. [J]. Journal of Chongqing Medical University 34(9):1280-1282(2009) DOI：

摘要

目的:分析急性胰腺炎肺功能改变的特点

并探讨其临床意义。方法:2007年1月至2009年6月入我院治疗的急性胰腺炎82例在确诊当天行肺功能检查

并以同期我院健康体检者80例作为对照。结果:急性胰腺炎反应肺通气功能的指标FVC、FEVI、FEVI/FVC、MVV等均没有明显改变（P

0.05）;而反应换气功能的DLCO、DLCO/VA和反映小气道功能的FEF25、FEF50、FEF75均有受损表现（P

0.05）。DLCO、DLCO/VA、FEF25、FEF50、FEF75均和Ranson标准及APACHEⅡ评分均呈负相关（P

0.05）。并且在急性胰腺炎肺损伤组和非肺损伤组肺换气功能指标有差异（P

0.05）

DLCO影响肺损伤发生的OR值为0.755

95%CI为0.689

.821。结论:急性胰腺炎患者存在一定程度的换气功能及小气道功能障碍

其障碍程度和病情严重程度相关;并且肺换气功能也可能是急性胰腺炎肺损伤判断的一个标准。

Abstract

Objective:To analyze the changes in pulmonary function test in patients with acute pancreatitis(AP)

and to explore its clinical significance. Methods: This study included 82 patients with AP and 80 healthy controls from January 2007 to June 2009 in our hospital. All participants were evaluated with pulmonary function test. Results: The FVC

FEVI

FEVI/FVC

MVV

which determine pulmonary ventilation function

were similar in the two groups(P>0.05). The DLCO

DLCO/VA

FEF25

FEF50

FEF75

which determines pulmonary gas exchange

revealed a statistically significant decline in patients with AP(P<0.05). DLCO

DLCO/VA

FEF25

FEF50

FEF75

negatively correlated with Ranson’s criteria(P<0.05)

as well as APACHE Ⅱ score. And DLCO

DLCO/VA

FEF25

FEF50

FEF75 showed differences between lung injury and non lung injury in patients with AP(P <0.05). The OR for DLCO affected lung injury was 0.755

95% CI was 0.689~0.821. Conclusion: Patients with AP have some degree of dysfunction in gas exchange

which related to the severity of AP; and pulmonary function tests may give additional prognostic information in patients with AP.

关键词

急性胰腺炎肺功能通气功能换气功能

Keywords

acute pancreatitisPulmonary function testsVentilation functionGas exchange function

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