Objective: To evaluate the Tramal-sparing effect and safety of Lornoxicam for pain relief following gynecological surgery.Methods: 60 ASA ⅠorⅡpatients aged 22～65 yr undergoing gynecological surgery under epidural anesthesia were randomly allocated to two groups: Lornoxicam group and control group(n=30).The PCIA pump was set up afer surgery

with 0.04%Lornoxicam+0.75%Tramal for Lornoxicam group and 1%Tramal for control group.The intensity of analgesia

adverse effects and blood clotting function were recorded and compared between the two groups.Results: The Tramal consumption and the number of successfully delivered doses at 12 and 24 h after operation were significantly less in Lornoxicam group than in control group.The VAS scores at 6

12 and 24 h after operation were significantly lower

and The patients’ global evaluation of the postoperative analgesia was better in Lornoxicam group.The adverse effects of nausea and vomiting were significantly less in Lornoxicam group Compared with these in control group

There was no difference in blood clotting function between the two groups.Conclusion:Combination of Lornoxicam and Tramal in postoperative analgesia following gynecological surgery may reduce the Tramal consumption and the adverse effects

accordingly elevate analgesia quality.