Objective:To retrospectively demonstrate risk factors for thoracic injuries with multiple trauma superinduct infection and study the relationship between interleukin and infection.Methods:230 patients having chest trauma with multiple trauma(91 superinduct infection and 139 uninfection)from January 2006 to June 2008 in department of cardiothoracic surgery

Chongqing emergency medical center were analyzed.This was a retrospective cohort study regarding multiple trauma as causes

and 32 items of potential risk factors of impacting mortality were calculated by univariate and multivariate logistic in order to find distinctive items in these patients and laboratory test.Results:The odds ratio(OR)and 95% confidence intervals(CI)of infection fate were associated with seven risk factors [multiple organs dysfunction syndrome scale

quantities of operation(≥2)

aspiration of gastric contents

associated head injury

pancreas injury

kidney injury

and gastrointestinal tract injury].The mean plasma concentration of IL-1β

TNFα

and IFN-γin the infection group were higher than those in the uninfection group respectively(1501.19±2186.06 pg/ml vs 1127.07±1755.43 pg/ml

5251.64±5554.46 pg/ml vs 5101.83±4357.64 pg/ml

181.97±276.18 pg/ml vs 34.89±108.42 pg/ml)(P <0.05).Conclusion:There were significant relationship between the MODS scale

associated head and abdominal injury

quantities of operation and infection complication in patients having chest trauma with multiple trauma.The plasma concentration of IL-1β

TNFα

and IFN-γof patients on the first day after injury could be the reference to judge patient’s in the later period.