Protective effects of sevoflurane on myocardial ischemia reperfusion injury

Xu Yiqing; Ni Xiaolin; Hu Runhui; Chen Heping

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Protective effects of sevoflurane on myocardial ischemia reperfusion injury

更新时间：2023-12-22

- Protective effects of sevoflurane on myocardial ischemia reperfusion injury
- Journal of Chongqing Medical University Vol. 43, Issue 3, Pages: 317(2018)
- 作者机构：
  
  1. 南昌大学第二临床医学院,南昌,330000
  2. 江西省基础药理学重点实验室,南昌,330000
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2018，
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Xu Yiqing, Ni Xiaolin, Hu Runhui, et al. Protective effects of sevoflurane on myocardial ischemia reperfusion injury. [J]. Journal of Chongqing Medical University 43(3):317(2018)
DOI：

Xu Yiqing, Ni Xiaolin, Hu Runhui, et al. Protective effects of sevoflurane on myocardial ischemia reperfusion injury. [J]. Journal of Chongqing Medical University 43(3):317(2018) DOI：

摘要

大量研究表明，七氟烷预处理和后处理，在心肌缺血再灌注中起到了心肌保护作用，而关于其作用机制，相关研究和争议颇多。本文就七氟烷在心肌缺血再灌注中的保护作用作一综述，为临床麻醉用药提供指导。同时指出七氟烷心肌保护作用在临床工作中所遇到的问题，并提出对未来研究的展望。

Abstract

Large amounts of experiments have proved that sevoflurane，both preconditioning and post-conditioning，has the cardio-protective effect. However，the specific mechanism of this effect has been studied a lot and is greatly disputed. This article reviews these mechanisms in the cardio-protective effect of sevoflurane. Meanwhile，theoretical bases for rational administration of sevoflurane during clinical anesthesia are provided. The application and its limitations of the cardio-protective effect of sevoflurane in the current clinical work，along with our expectations are also put forward.

关键词

七氟烷缺血再灌注损伤心肌保护作用机制临床应用

Keywords

sevofluraneischemia reperfusion injurymyocardial protective effectmechanismsclinical application

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