Objective：To explore the clinical features，etiology，diagnosis and treatment of acute pancreatitis in pregnancy. Methods：From January 2010 to December 2016，16 patients with acute pancreatitis were enrolled in this study，and the data of clinical fea－tures，biochemical examination，B-mode ultrasound，computed tomography，therapeutic process and prognosis were retrospectively analyzed. Results：Fourteen cases were diagnosed as mild acute pancreatitis and 2 were as severe acute pancreatitis patients. Eleven of the total 16 patients had maternal live babies. In patients with mild acute pancreatitis，9 cases had fetal maturity（8 had cesarean section termination，1 had vaginal delivery）. For the other 5 cases whose gestational age were smaller，the disease symptoms were improved after conservative treatment. Two patients with severe acute pancreatitis who had hyperlipidemia ended pregnancy by cesarean section and were treated by internal medicine and discharged from hospital. Conclusion：The main pathogeny of pregnancy complicated acute pancreatitis are bile duct disease and hyperlipidemia. Blood，urine amylase and imaging examination are commonly used clinical examination at current. On the base of patients’ safety，individualized therapy should be adopted according to their clinical feature.