Objective：To investigate the feasibility and accuracy of high-resolution three-dimensional contrast-enhanced magnetic resonance venography（3D CE-MRV） combined with three-dimensional T1-weighted magnetic resonance imaging（3D T1-weight MRI） in surgical planning for stereotactic electroencephalography. Methods：A total of 12 patients with medically intractable epilepsy who planned to undergo SEEG surgery were enrolled. Individualized MRI was performed，and the iPlan software was used to develop surgi－cal plans. A total of 89 electrodes were implanted，and the results of the surgery were analyzed. Results：The 89 electrodes were successfully implanted，and no postoperative bleeding was observed. Of all patients，2 had insular epilepsy. Conclusion：High-resolu－tion 3D CE-MRV helps to find the avascular trajectory and 3D T1-weight MRI helps to know the structure of brain tissue in the avascular trajectory. Their combination can accurately develop the surgical plan and reduce complications.