Objective：To explore the distribution characteristics of inhaled allergen in Chongqing area and to provide references for preventing allergic diseases. Methods：All cases were collected from the Children’s Hospital Affiliated to Chongqing Medical Univer－sity from May 2005 to December 2009.13 841 children with allergic diseases underwent skin prick test（SPT）. The distribution char－acteristics were analyzed by SPSS 17.0. Results：The total positive rate of allergen was 80.3%，of which Dermatophagoides farinae（Der f） was the highest （67.6%），then followed by Dermatophagoides pteronyssinus（Der p）（67.5%） and Blomia tropicalis（42.8%）.From May 2005 to December 2009，the positive rate and positive degree of the 3 kinds of mites were stable except in 2006. With the age increasing，the positive rate ascended in mites（Der f，Der p，Blomia tropicalis），American cockroach，Blatella germanica，cat hair and dog dander，but PollenⅠ，Mycetes Ⅳ and ragweed showed opposite tendency. The 13 categories sensibiligen could be divided into 4 clusters：Der p and Der f，Blomia troplis，Blatella germanica，and others. Conclusion：Dermatophagoides farinae，Dermatophagoides pteronyssinus and Blomia tropicalis are the most prevalent allergens in Chongqing area in the past 5 years. The different age groups show different reactions in SPT. The clinical characters of Blomia troplis are different from Der p and Der f，and specific immune ther－apy that points to Blomia troplis in subtropical areas should be paid attention.