Objective：To explore the curative effect of ectogenesis osteoinduction growth factor（ossotide for injection） in treatment of distal radius fracture. Methods：Totally 74 cases of distal radius fracture were randomly divided into treatment group and control group. Ossotide for injection（30 mg） was used in treatment group while calcium carbonate tablets were used in control group. Bone density，biochemical indicator of bone metabolism and fracture recovery were measured. Results：All cases were followed up for 6-8 months（7.1 months in average）. Serum bone alkaline phosphatase（BALP），procollagen typeⅠcarboxyterminal propeptide（PICP），bone gla protein（BGP） and bone density of healthy radius were significantly higher in treatment group than in control group at 2 months after treatment（P<0.05）. The average recovery time was （8.5±2.7） weeks in treatment group，significantly higher than that of （11.8±3.1） weeks in control groups. The effective rate was 85.3%，significantly higher than that of 28.9% in control group（P<0.05）. Con－clusions：Ossotide for injection can increase bone inducibility and bone mass and enhance fracture recovery for elderly patients.