Relationship between clinical and electroencephalographic characteristics of febrile seizures and subsequent epilepsy
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Relationship between clinical and electroencephalographic characteristics of febrile seizures and subsequent epilepsy
Journal of Chongqing Medical UniversityVol. 37, Issue 11, Pages: 972-975(2012)
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南京医科大学附属南京儿童医院神经内科,南京,210008
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Published:2012,
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CHEN Jing, ZHENG Guo, GUO Hu, et al. Relationship between clinical and electroencephalographic characteristics of febrile seizures and subsequent epilepsy. [J]. Journal of Chongqing Medical University 37(11):972-975(2012)
DOI:
CHEN Jing, ZHENG Guo, GUO Hu, et al. Relationship between clinical and electroencephalographic characteristics of febrile seizures and subsequent epilepsy. [J]. Journal of Chongqing Medical University 37(11):972-975(2012)DOI:
Relationship between clinical and electroencephalographic characteristics of febrile seizures and subsequent epilepsy
Objective:To investigate the electroencephalographic characteristics of febrile seizures(FS) and to indicate the relationship between abnormity of electroencephalogram(EEG) and subsequent epilepsy occurrence. Methods:Totally 165 patients with FS were referred from the outpatient and inpatient department for video-electroencephalogram(VEEG) within 7-20 d after the seizure. VEEGs were classified as paroxysmally abnormal based on the presence of spikes,sharp waves or spike-wave complexes. The relationship between paroxysmally abnormal EEG and subsequent epilepsy occurrence was discussed. Results:Of the 165 patients with FS,60(36.36%) revealed paroxysmal abnormality on VEEG and 45(75%) developed epilepsy. The abnormal rate of VEEG was closely re-lated with age,family history of EP,fever temperature,FS type,types of seizures,more than one seizure within 24 h and the duration of seizures. Of the 8 patients with generalized paroxysmal spike and wave activity,2(25%) developed epilepsy. Of the 14 patients with rolandic discharge(RD),9(64.3%) developed epilepsy. Of the 21 patients with paroxysms in the occipital region,18(85.7%) developed epilepsy. Of the 17 patients with paroxysms in the frontal region,16(94.1%) developed epilepsy. Compared with general-ized EEG foci,the relative risk(RR) for patients with frontal EEG foci was 48.0. Patients with frontal EEG paroxysms had signifi-cantly higher risk of developing epilepsy than those with paroxysms in other regions of EEG foci(P=0.003). Conclusion:These find-ings suggest that patients with FS presenting frontal paroxysmal EEG abnormalities may be at risk for epilepsy.
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热性惊厥视频脑电图预后癫痫额区
Keywords
febrile seizurevideo-electroencephalogramprognosisepilepsyfrontal region