Objective To study the association between autonomic dysfunction and the level of plasma norepineprine and acetylcholine in acute phase of cerebralhemorrhage patients.Methods To analyze 45 patients with initial cerebral hemorrhage in different sites and 38 healthy man.Fasting 3ml venous blood was taken and put in the anticoagulant tube precooled at the second and tenth days after admission. Centrifuged at 4 ℃

The supernatant was set below -70 ℃. To detect plasma norepineprine level with cerebral hemorrhage group and control group by liquid chromatography-mass spectrometry

and acetylcholine level by enzyme-linked immunosorbent assay;Recording autonomic dysfunction symptoms with patients;To evaluate cerebral infarction patients neurologic impairment by NIHSS.Results The level of plasma norepineprine