Objective：To summarize the epidemiology and clinical feathers of rabies in children. Methods：Clinical data of 53 diag－nosed rabies cases in the Children’s Hospital of Chongqing Medical University from November 2006 to December 2011 were retro－spectively analyzed. Results：Age of the 53 children was from 1 year and 3 months to 14 years with an average of 7.5 years. Gender ratio was 2.31∶1. Among the 47 cases which had clearly exposure history，43 were attacked by dogs and 4 scratched by cats；only 7 did rabies vaccination and 1 treated the wound in hospital after the bite，none took immunoglobulin. According to clinical manifesta－tion，77.36% had fever，69.81% had hydrophobia and fear of wind，33.96% had hyperspasmia. Nineteen patients died in hospital，of which 4 did autopsy. Parents of 34 patients gave up the therapy. Conclusions：Rabies is a zoonosis with high mortality and poor prog－nosis；children are of high risk and should be timely realized by parents and doctors.