Objective：To compare therapeutic effects between proximal femoral locking compression plate（LCP） and proximal femoral nail antirotation（PFNA） in the treatment of femoral intertrochanteric fractures. Methods：Totally 125 patients with intertrochanteric fractures from 2005 to 2011were enrolled and were randomly divided into two groups. Patients in the two groups were treated with PF－NA and proximal femoral LCP respectively. Follow-up was conducted for 12-24 months，averaged 18.2 months. Condition during the operation and after operation was compared between two groups. Results：There was no significant difference in general data between the two groups（P >0.05）. There were significant differences in length of incision，blood loss，bed-lying time and postoperative drainage between two groups（P<0.05）. There was no significant difference in operation time，fracture healing time，Harries score and compli－cations between two groups（P>0.05）. Conclusions：For the treatment of intertrochanteric femoral fracture，both proximal femoral LCP and PFNA fixation could achieve good outcome，however，PFNA has more advantages in treating unstable femoral intertrochanteric fractures.