Objective：To explore the effect of alcohol drinking on male sperm quality. Methods：Literatures on the relationship between drinking and male sperm quality were reviewed by conducting Meta analysis. Results：Six controlled studies on alcohol drinking and male infertility were included. Three aspects including sperm density（SD），sperm energy a+b（SEa+b），rate of teratospermia（RT） were focused. Combined mean differences（MDs） were -1.81（95%CI＝-4.68 to 1.06） in SD and -8.39（95%CI＝-19.22 to 2.43） in SEa+b；the difference of SD and SEa+b between drinking and non-drinking was not statistically significant：MD was 7.20（95%CI＝1.62 to 12.78） in RT，the difference of RT between drinking and non-drinking were statistically significant in Meta analysis. Conclusions：Alcohol drinking is a risk factor for male infertility and its main harm was to increase the RT.