Objective：To evaluate the preliminary efficacy of nano-hydroxyapatite/polyamide 66（n-HA/PA66） cage in reconstruction following anterior cervical intervertebral discectomy and fusion in cervical spondylosis. Methods：Clinical data of 46 patients with cer－vical spondylopathy and cervical disc herniation who underwent anterior cervical intervertebral discectomy and fusion between June 2008 and June 2011 were retrospectively analyzed. Cervical pathologies included cervial spondylotic myelopathy and cervical radicu－lopathy. All patients were assessed clinically and radiologically. Clinical outcome was evaluated using Odom’s criteria；radiology results included subsidence of the cages，angle of cervical lordosis，fusion rate and intervertebral height. Results：Based on Odom’s criteria，excellent rate was 80%. All cases achieved graft fusion at 6 months after the operation without displacement and subsidence. There were significant differences in angle of cervical lordosis between preoperation and 6 months after operation（（2.29±3.04）° vs. （8.04±3.06）°，P＜0.05）；last follow-up showed（6.58±2.35）° and the mean loss of angle of cervical lordosis was （1.45±1.96）°. There were significant differences in intervertebral height between preoperation and at 6 months after the operation（（7.76±0.55） mm vs. （4.40±1.36） mm，P＜0.05）；last follow-up showed（7.36±0.59） mm and the mean loss of intervertebral height was （0.41±0.28） mm. Conclusions：n-HA/PA66 cage is effectively in the reconstruction following anterior cervical intervertebral discectomy and fusion since it can effec－tively maintain the biological alignment and cervical intervertebral height with high fusion rate.