Objectives：To compare therapeutic effect and complication of tension-free vaginal tape（TVT） and tension-free vaginal tape-obturator（TVT-O） in the treatment of stress urinary incontinence. Methods：Totally 137 female patients with stress urinary incontinence from October 2002 to October 2011 in department of urology in our hospital were randomized into two groups. TVT-O and TVT were used in two groups respectively. Urinary control situation，surgical time，perioperative complications including bladder injury，urinary retention，overactive bladder syndrome，etc and hospitalization time at 12 months after the surgery were focused on. Results：All pa－tients completed the 12-month’s follow-up. Average operative time in TVT-O group was significantly shorter than that in TVT group. Perioperative complication rate was significantly higher in TVT group than in TVT-O group. There was no difference in blood loss and hospitalization time between the two groups. Curative rate at 12 months after surgery was 93.33% in TVT group and 94.81% in TVT-O group；the overall curative rate was 94.16%. Conclusion：Both methods are equally effective in the treatment of female stress urinary incontinence. However，TVT-O had shorter operative time and lower overall perioperative complication rate.