MicroRNA-21 in organ fibrosis

Wen Li; Zhang Zheng

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MicroRNA-21 in organ fibrosis

更新时间：2023-12-18

- MicroRNA-21 in organ fibrosis
- Journal of Chongqing Medical University Vol. 38, Issue 5, Pages: 638-641(2014)
- 作者机构：
  
  1. 重庆医科大学 1. 基础医学院细胞生物学教研室
  2. 基础医学院遗传学教研室
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2014，
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Wen Li, Zhang Zheng. MicroRNA-21 in organ fibrosis. [J]. Journal of Chongqing Medical University 38(5):638-641(2014)
DOI：

Wen Li, Zhang Zheng. MicroRNA-21 in organ fibrosis. [J]. Journal of Chongqing Medical University 38(5):638-641(2014) DOI：

摘要

器官纤维化是多种因素引起的急性或慢性病理变化，如若得不到有效治疗最终会导致器官功能衰竭。近年来，关于microRNA的研究越来越受到重视，尤其是microRNA-21（miR-21），作为一种小分子调节RNA，在多种疾病包括癌症、心血管疾病、器官纤维化等的发生过程中发挥重要作用。本文就miR-21在各种纤维化疾病中的作用作一综述。

Abstract

Organ fibrosis is acute or chronic pathological changes caused by a variety of factors. Lack of effective treatment will even－tually lead to organ failure. In recent years，the study of microRNA receives more and more attention. Especially microRNA-21，as a small molecule regulating RNA，plays an important role in the occurrence of a variety of diseases，including cancer，cardiovascular disease，organ fibrosis. This paper reviewed microRNA-21 in various fibrotic diseases.

关键词

microRNA-21小分子纤维化

Keywords

microRNA-21small moleculesfibrosis

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