Objective：To explore the effects of positive pressure connector on central venous pressure（CVP） testing by peripherally in－serted central catheter（PICC），to reduce the measuring errors of CVP and to provide more accurate data for doctors. Methods：CVP of 51 patients inserted PICC in our department before and after connecting positive pressure connector was measured and compared. Results：There was no significant difference in CVP data before and after connecting positive pressure connector（P=0.417）. Conclu－sion：Positive pressure connector exerts no significant effect on CVP testing by PICC and it is advised to measure CVP by PICC with positive pressure connector in clinics.