Application of aspiration thrombectomy during ST-segment elevation of acute myocardial infarction：a systematic review

Ran Yang; He Xiaojiao2; Yang Yuan3; Lyu Zi4; Luo Suxin5

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Application of aspiration thrombectomy during ST-segment elevation of acute myocardial infarction：a systematic review

更新时间：2023-12-18

- Application of aspiration thrombectomy during ST-segment elevation of acute myocardial infarction：a systematic review
- Journal of Chongqing Medical University Vol. 40, Issue 2, Pages: 296-301(2015)
- 作者机构：
  
  1. 重庆医科大学附属第一医院心血管内科,重庆,400016
  2. 四川大学华西临床医学院,成都,610041
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2015，
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Ran Yang, He Xiaojiao2, Yang Yuan3, et al. Application of aspiration thrombectomy during ST-segment elevation of acute myocardial infarction：a systematic review. [J]. Journal of Chongqing Medical University 40(2):296-301(2015)
DOI：

Ran Yang, He Xiaojiao2, Yang Yuan3, et al. Application of aspiration thrombectomy during ST-segment elevation of acute myocardial infarction：a systematic review. [J]. Journal of Chongqing Medical University 40(2):296-301(2015) DOI：

摘要

目的：评价急性ST段抬高型心肌梗死（ST-segment elevation of acute myocardial infarction，STEMI）患者中应用血栓抽吸术的临床疗效。方法：通过在PubMed、CNKI、维普、万方等数据库中检索关于急性STEMI行血栓抽吸联合冠脉支架介入治疗与单纯冠脉支架介入治疗的随机对照研究文献，根据纳入/排除标准筛选文献，利用 RevMan 5.2软件进行Meta分析。结果：共纳入13项研究，通过血栓抽吸联合冠脉支架介入治疗与单纯冠脉支架介入治疗对比，全因死亡率无统计学差异（RR=0.85，95%CI=0.73～1.00，P=0.05），但血栓抽吸组主要心血管不良事件（major adverse cardiovascular events，MACE）事件发生率明显低于单纯PCI组（RR=0.81，95%CI=0.68～0.97，P=0.02）。结论：对于急性STEMI的患者行血栓抽吸能减少患者MACE事件发生率，对远期生存率有着积极作用。

Abstract

Objective：To systematically review the clinical efficacy of aspiration thrombectomy during ST-segment elevation of acute myocardial infarction（STEMI）. Methods：Literature search was performed among Pubmed，CNKI，VIP，Wangfang databases to search for available randomized control trials comparing aspiration thrombectomy combined with percutaneous coronary intervention（PCI） and single PCI. The Meta-analysis was conducted by using RevMan 5.2 software. Results：Totally 13 trials concerning 11 823 patients were enrolled. There was no statistically significant difference in all-cause mortality between aspiration thrombectomy combined with PCI and single PCI（RR=0.85，95%CI=0.73 to 1.00，P=0.05）. Major adverse cardiac events（MACE） was significantly reduced in aspira－tion thrombectomy combined with PCI than in single PCI（RR=0.81，95%CI=0.68 to 0.97，P=0.02）. Conclusion：Aspiration thrombec－tomy is conducive to reducing MACE.

关键词

急性心肌梗死血栓抽吸冠脉支架介入治疗Meta分析系统评价

Keywords

acute myocardial infarctionaspiration thrombectomypercutaneous coronary interventionMeta-analysissystematic re－view

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