New application of salicylates in improving glucose metabolism in patients with type 2 diabetes mellitus

Jiang Xin; Liu Fang; Deng Huacong

您当前的位置：

首页 >

文章列表页 >

New application of salicylates in improving glucose metabolism in patients with type 2 diabetes mellitus

更新时间：2023-12-18

- New application of salicylates in improving glucose metabolism in patients with type 2 diabetes mellitus
- Journal of Chongqing Medical University Vol. 40, Issue 7, Pages: 1029-1031(2015)
- 作者机构：
  
  重庆医科大学附属第一医院内分泌科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2015，
扫描看全文
Jiang Xin, Liu Fang, Deng Huacong. New application of salicylates in improving glucose metabolism in patients with type 2 diabetes mellitus. [J]. Journal of Chongqing Medical University 40(7):1029-1031(2015)
DOI：

Jiang Xin, Liu Fang, Deng Huacong. New application of salicylates in improving glucose metabolism in patients with type 2 diabetes mellitus. [J]. Journal of Chongqing Medical University 40(7):1029-1031(2015) DOI：

摘要

慢性低度炎症参与胰岛素抵抗及2型糖尿病的发生发展。临床资料显示经典的水杨酸类抗炎药能有效改善2型糖尿病患者糖代谢状态，但其具体作用机制尚不明确。研究表明，除了抑制炎症反应外，水杨酸类药物还能通过减轻氧化应激、激活腺苷酸活化蛋白激酶、降低游离脂肪酸水平等多种途径发挥降糖效应。本文就近年来水杨酸类药物对糖代谢作用的研究成果进行综述，从而为该类药物在2型糖尿病应用中的深入研究提供新的思路。

Abstract

Chronic low-grade inflammation participates in the pathogenesis of insulin resistance and type 2 diabetes mellitus. Clinical data show that salicylates can improve glucose metabolism in patients with type 2 diabetes. However，its hypoglycemic mechanism is unclear. Some studies have indicated that in addition to inhibiting inflammation，salicylates can reduce glycemia through other ways such as alleviating oxidative stress，activating AMP-activated protein kinase and decreasing free fatty acid level. This article reviewed the literature in recent years about the effect of salicylates on glucose metabolism，which will provide new ideas for the further studies of the application of salicylates in type 2 diabetes mellitus.

关键词

水杨酸2型糖尿病炎症

Keywords

salicylatetype 2 diabetes mellitusinflammation

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

A clinical study of cardiac autonomic neuropathy with retinopathy and nephropathy in patients with type 2 diabetes mellitus

Influence of type 2 diabetes mellitus on the morphology and apoptosis of germ cells in male mice

Endothelial-overexpressed lipopolysaccharide-associated factor 1 promotes skin wound healing in diabetic mice by affecting the nuclear factor-kappa B signaling pathway

Research progress of molecular mechanism of palmitic acid-induced pancreatic β-cell dysfunction

Protective effect of sodium aescinate against hydronephrosis injury in mice after unilateral ureteral obstruction

Related Author

Tian Lina

Niu Ben

Zhu Enxian

Xie Yajuan

Li Chong

Xie Xi

Wang Yaru

Liu Yu

Related Institution

The First College of Clinical Medicine，Yunnan University of Chinese Medicine

Department of Endocrinology，The First People’s Hospital of Yunnan Province/Affiliated Hospital of Kunming University of Science and Technology

NHC Key Laboratory of Hormones and Development，Tianjin Key Laboratory of Metabolic Diseases，Tianjin Institute of Endocrinology，Department of Clinical Laboratory，Chu Hsien-I Memorial Hospital，Tianjin Medical University

Department of Endocrinology，The First Affiliated Hospital of Army Medical University

College of Traditional Chinese Medicine,Shandong University of Traditional Chinese Medicine

⁰