The value of using uterine artery Doppler parameters at the first trimester pregnancy to predict pregnancy outcomes in a low-risk population
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The value of using uterine artery Doppler parameters at the first trimester pregnancy to predict pregnancy outcomes in a low-risk population
Journal of Clinical Ultrasound in MedicineVol. 24, Issue 10, (2022)
作者机构:
1. 上海交通大学医学院附属国际和平妇幼保健院,上海,200030
2. 上海市胚胎源性疾病重点实验室,上海,200030
3. 上海交通大学医学院出生缺陷与罕见病临床研究院,上海,200030
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Published:2022,
Published Online:31 October 2022,
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The value of using uterine artery Doppler parameters at the first trimester pregnancy to predict pregnancy outcomes in a low-risk population. [J]. Journal of Clinical Ultrasound in Medicine 24(10).(2022)
DOI:
The value of using uterine artery Doppler parameters at the first trimester pregnancy to predict pregnancy outcomes in a low-risk population. [J]. Journal of Clinical Ultrasound in Medicine 24(10).(2022)DOI:
The value of using uterine artery Doppler parameters at the first trimester pregnancy to predict pregnancy outcomes in a low-risk population
Objective The aims of this study were to establish the normal reference range of uterine artery doppler parameters at the generation of 11~13+6 weeks in low risk population,and to evaluate its value in predicting pregnancy outcomes. Methods The Doppler parameters of bilateral uterine artery including pulsatility index (PI),resistance index (RI) and the presence or absence of early diastolic notching were examined by abdominal ultrasonography at 11~13+6 weeks of pregnancy,and the demographic characteristics and pregnancy outcome were collected. The above related parameters were statistically analyzed. Results A total of 800 patients were eligible for inclusion in this study,including 740 patients in the normal pregnancy outcome group and 60 patients in the adverse pregnancy outcome group. With the exception of body maternal index,fetal gestational age and birth weight at delivery,there was no difference in demographic characteristics between the two groups of pregnancy outcome (P<0.05).The mean pulsatility index (mPI) and mean resistence index (mRI) show a progressive decline from 11 to 13+6 weeks,the prevalence of bilateral notching was gradually decreased with the increase of gestational age. The area under the curve (AUC) of mPI,mRI and bilateral notching for predicting pregnancy outcome was 0.542,0.574 and 0.521,respectively,and the AUC of the combination of the three parameters for predicting pregnancy outcome was 0.648.The results of the ROC curve analysis demonstrated the prognostic value of the combination of BMI,age,mPI,mRI and bilateral notching was 0.751.Conclusions The normal reference range of uterine artery doppler parameters was established in the low risk population at 11 to 13+6 weeks of pregnancy.There is limited value in using only uterine artery doppler parameters to predict pregnancy outcomes at 11–13+6 weeks gestation.A combination of clinical characteristics and uterine artery Doppler ultrasound can more effectively predict adverse pregnancy outcomes in low risk population.
关键词
早孕期子宫动脉多普勒阻力指数搏动指数妊娠结局
Keywords
first trimesterUterine arteryDopplerpulsatility indexresistance indexPregnancy outcome
Color Doppler Ultrasound of Uterine Artery and Internal Iliac Artery of Pregnant Women in the Second trimester Value in judging adverse pregnancy outcome
Dynamic change rules of umbilical artery Doppler spectrum in fetal abdomen and its relationship with pregnancy outcomes of puerperae with hypertensive disorder complicating pregnancy
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