Objective To investigate the predictive value of left atrial phase function for left ventricular diastolic dysfunction in patients with coronary heart disease. Methods According to the guidelines

89 CHD patients with left ventricular ejection fraction (LVEF) ≥50% were divided into LV diastolic normal group (38 cases) and LVDD group (51 cases). Cardiac structural parameters were measured and parameter differences were compared between the two groups.The independent influencing factors of LVDD were screened out by binary Logistic regression

and ROC curve was drawn to evaluate the predictive value of each independent influencing factor on LVDD. Results There were no significant differences in LVEF

LVEDd

LVEDV

IVSDd

LVPWDd and TR between the two groups (ALL P>0.05). The mitral annulus interval E "

the lateral wall E "

LAVI and E/ E "of mitral annulus in the normal LV diastolic function group were lower than those in the LVDD group

and the differences were statistically significant (P<0.05).LASr and LAScd in LV group with normal diastolic function were higher than those in LVDD group

the difference was statistically significant (P<0.001)

but there was no significant difference in LASct between LV group and LVDD group (P>0.05).Binary Logistic regression analysis showed that LASr (OR=0.668

95%CI: 0.570-0.783

P<0.001) and LAScd (OR=0.670

95%CI:0.565-0.796

P<0.001) were independent influencing factors of LVDD in CHD patients.The area of mitral annulus interval E "under ROC curve was 0.623 (95%CI:0.505-0.740)

the sensitivity was 94.7%

the specificity was 45.1%

and the cut-off value was 7.35.The area of e "under ROC curve was 0.0.662 (95%CI:0.547-0.777)

the sensitivity was 78.9%

the specificity was 62.7%

and the cut-off value was 10.25.LAVI had an area of 0.807 (95%CI:0.712-0.902) under ROC curve

a sensitivity of 76.5%

a specificity of 78.9%

and a cut-off value of 33.50.The area of E/ E "under ROC curve was 0.818 (95%CI:0.732-0.905)

the sensitivity was 66.7%

the specificity was 84.2%

and the cut-off value was 13.45.The area under ROC curve of LASr was 0.928 (95%CI:0.874~0.982)

the sensitivity

specificity and cut-off value were 86.8%

90.2% and 32.25%

respectively.The area under ROC curve of LAScd was 0.914 (95%CI:0.855-0.973)

the sensitivity was 86.8%

the specificity was 84.3%

and the cut-off value was 15.50%.Conclusion Changes in LA function can suggest LVDD in LVEF≥50% of CHD patients. LASr and LAScd are independent influencing factors of LVDD in CHD patients

and LASr has high predictive value.