Research Progress of Ultrasound Targeted Microbubble Destruction Technology Mediated Suicide Genes in Malignant Tumors

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Research Progress of Ultrasound Targeted Microbubble Destruction Technology Mediated Suicide Genes in Malignant Tumors

更新时间：2023-10-11

- Research Progress of Ultrasound Targeted Microbubble Destruction Technology Mediated Suicide Genes in Malignant Tumors
- Journal of Clinical Ultrasound in Medicine Vol. 24, Issue 5, (2022)
- 作者机构：
  
  中国医科大学附属盛京医院
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2022，
  
  Published Online：27 May 2022，
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Research Progress of Ultrasound Targeted Microbubble Destruction Technology Mediated Suicide Genes in Malignant Tumors. [J]. Journal of Clinical Ultrasound in Medicine 24(5).(2022)
DOI：

Research Progress of Ultrasound Targeted Microbubble Destruction Technology Mediated Suicide Genes in Malignant Tumors. [J]. Journal of Clinical Ultrasound in Medicine 24(5).(2022) DOI：

摘要

恶性肿瘤是全球发病率和死亡率的一个重要原因

严重威胁人类的健康。作为其常规的治疗方法

化疗、放疗和手术仍有局限性。自杀基因疗法为各种形式的恶性肿瘤提供了一种极具前景的治疗手段。超声靶向微泡破坏(UTMD)技术为自杀基因的传递赋予了新的方式。本文着重就 UTMD 介导的自杀基因转染在恶性肿瘤治疗中的最新进展进行总结并对其未来发展提出展望。

Abstract

Malignant neoplasm is an important cause of morbidity and mortality worldwide

which poses a serious threat to human health. As its conventional treatment methods

chemotherapy

radiotherapy and surgery still have limitations. Suicide gene therapy offers a highly promising treatment for various forms of malignancy. The ultrasound targeted microbubble destruction technology (UTMD) provides a new way for suicide gene delivery. This article focuses on summarizing the latest progress of UTMD-mediated suicide gene transfection in the treatment of malignant tumors and presenting prospects for its future development.

关键词

超声靶向微泡破坏技术自杀基因微泡载体恶性肿瘤

Keywords

Ultrasound targeted microbubble destructionsuicide genesMicrobubble carrierMalignant tumor

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