Analysis of the application value of ultrasonography in the differential diagnosis of idiopathic precocious puberty and the evaluation of curative effect of true precocious puberty in girlsYu jia1, Zeng Xue-lian2, Zhang Zong-hua3, Liu Wei-ying1, Liu Ping1

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Analysis of the application value of ultrasonography in the differential diagnosis of idiopathic precocious puberty and the evaluation of curative effect of true precocious puberty in girlsYu jia1, Zeng Xue-lian2, Zhang Zong-hua3, Liu Wei-ying1, Liu Ping1

更新时间：2023-10-11

- Analysis of the application value of ultrasonography in the differential diagnosis of idiopathic precocious puberty and the evaluation of curative effect of true precocious puberty in girlsYu jia1, Zeng Xue-lian2, Zhang Zong-hua3, Liu Wei-ying1, Liu Ping1
- Journal of Clinical Ultrasound in Medicine Vol. 23, Issue 6, (2021)
- 作者机构：
  
  1. 彭州市人民医院
  2. 成都市新都区妇幼保健院
  3. 彭州市妇幼保健院
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2021，
  
  Published Online：29 June 2021，
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Analysis of the application value of ultrasonography in the differential diagnosis of idiopathic precocious puberty and the evaluation of curative effect of true precocious puberty in girlsYu jia1, Zeng Xue-lian2, Zhang Zong-hua3, Liu Wei-ying1, Liu Ping1. [J]. Journal of Clinical Ultrasound in Medicine 23(6).(2021)
DOI：

Analysis of the application value of ultrasonography in the differential diagnosis of idiopathic precocious puberty and the evaluation of curative effect of true precocious puberty in girlsYu jia1, Zeng Xue-lian2, Zhang Zong-hua3, Liu Wei-ying1, Liu Ping1. [J]. Journal of Clinical Ultrasound in Medicine 23(6).(2021) DOI：

摘要

目的：探讨超声检查在特发性性早熟女童鉴别诊断及真性性早熟女童疗效评估中的应用价值。方法：将我院2016年6月-2019年5月收治的86例特发性性早熟女童纳入研究

根据促性腺激素释放激素(GnRH)激发实验结果将所有患儿分成真性组(中枢性性早熟)52例及与假性组(外周性性早熟)34例

另取同期30例健康女童作为对照组。比较三组子宫以及卵巢超声检查结果。此外

真性组女童采用促性腺激素释放激素类似物(GnRHa)治疗

比较治疗前与治疗8个月后子宫以及卵巢超声检查结果。结果：真性组卵巢长径、卵巢横径、卵巢前后径以及最大卵泡直径均大于假性组与对照组(均P＜0.05)；而假性组与对照组上述各项指标水平对比均无统计学差异(均P＞0.05)。真性组子宫长径、子宫横径、子宫前后径均大于假性组与对照组

且假性组上述指标均大于对照组(均P＜0.05)。真性组治疗后卵巢长径、卵巢横径、卵巢前后径以及最大卵泡直径小于治疗前(均P＜0.05)。真性组治疗后子宫长径、子宫横径、子宫前后径均小于治疗前(均P＜0.05)。结论：超声检查下特发性性早熟女童的子宫和卵巢均存在明显增大

且在真性性早熟女童中此特征更加明显

其可辅助评估真性性早熟女童的治疗效果。

Abstract

Objective: To explore the application value of ultrasound in the differential diagnosis of idiopathic precocious puberty and the evaluation of curative effect of true precocious puberty in girls. Methods: 86 cases of girls with idiopathic precocious puberty who were admitted to our hospital from June 2016 to May 2019 were included in the study. According to the results of the gonadotropin-releasing hormone (GnRH) stimulation experiment

all the children were divided into the 52 cases with the true group (central precocity) and 34 cases with the sham group (peripheral precocity)

and 30 healthy girls in the same period were selected as the control group. The results of uterine and ovarian ultrasound examination were compared in the three groups. In addition

the girls in the true group were treated with gonadotropin-releasing hormone analogue (GnRHa)

and the results of uterine and ovarian ultrasound examination were compared before and 8 months after treatment. Results: The length diameter

transverse diameter

anteroposterior diameter and maximum follicular diameter of the true group were all larger than those of the sham group and the control group (all P<0.05). There was no statistical difference of the above indicators levels between the sham group and the control group (all P＞0.05). The length diameter

transverse diameter and anteroposterior diameter of the true group were all greater than those of the sham group and the control group

and the above indicators of the sham group were all greater than those of the control group (all P<0.05). After treatment

the length diameter

transverse diameter

anteroposteric diameter and maximum follicular diameter of the ovary in the true group were smaller than those before treatment (all P<0.05). After treatment

the length diameter

transverse diameter and anteroposterior diameter of the uterus of the true group were all smaller than those before treatment (all P< 0.05). Conclusion: Under ultrasound examination

the uterus and ovaries of idiopathic precocious puberty girls are significantly enlarged

and this feature is more obvious in true precocious puberty girls

which can assist to evaluate the therapeutic effect of true precocious puberty girls.

关键词

特发性性早熟诊断超声疗效评估

Keywords

Idiopathic precocityDiagnosisUltrasoundCurative effect evaluation

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