Value Of Contrast-Enhanced Ultrasound Combined With C-TIRADS Classification  In The Differential Diagnosis Of Thyroid Nodules

FU QIANG

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Value Of Contrast-Enhanced Ultrasound Combined With C-TIRADS Classification In The Differential Diagnosis Of Thyroid Nodules

更新时间：2023-10-11

- Value Of Contrast-Enhanced Ultrasound Combined With C-TIRADS Classification In The Differential Diagnosis Of Thyroid Nodules
- Journal of Clinical Ultrasound in Medicine Vol. 25, Issue 7, (2023)
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- Published：2023，
  
  Published Online：31 July 2023，
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FU QIANG. Value Of Contrast-Enhanced Ultrasound Combined With C-TIRADS Classification In The Differential Diagnosis Of Thyroid Nodules. [J]. Journal of Clinical Ultrasound in Medicine 25(7).(2023)
DOI：

FU QIANG. Value Of Contrast-Enhanced Ultrasound Combined With C-TIRADS Classification In The Differential Diagnosis Of Thyroid Nodules. [J]. Journal of Clinical Ultrasound in Medicine 25(7).(2023) DOI：

摘要

目的探讨超声造影（CEUS）联合中国版甲状腺影像报告与数据系统（C-TIRADS）分类对甲状腺结节良恶性的鉴别诊断价值。方法选取行甲状腺常规超声和超声造影检查的116位患者121个甲状腺结节，进行C-TIRADS分类和超声造影评估。以手术病理和细针穿刺（FNA）活检病理结果作为金标准。绘制受试者工作特征（ROC）曲线，比较C-TIRADS分类、CEUS评分法及两者联合对甲状腺结节的诊断效能。结果 C-TIRADS分类、CEUS评分和联合诊断ROC曲线的曲线下面积（AUC）分别为0.820、0.824、0.886，最佳分类阈值分别为4C类、2分、4C类。CEUS联合C-TIRADS分类的ROC曲线下面积（AUC）高于单独应用C-TIRADS分类和CEUS评分（Z=3.183，P<0.01；Z=2.070，P=0.038）。结论超声造影对C-TIRADS 4类结节有校正价值。CEUS联合C-TIRADS分类有助于提高甲状腺结节良恶性诊断效能。

Abstract

Objective To evaluate the value of contrast-enhanced ultrasound (CEUS) combined with C-TIRADS classification in the diagnosis of benign and malignant thyroid nodules. Methods A total of 116 patients with 121 thyroid nodules who underwent ultrasound examination and contrast-enhanced ultrasound were selected for C-TIRADS classification and contrast-enhanced ultrasound evaluation

using surgical pathology findings and fine-needle aspiration (FNA) biopsy pathology as the gold standard. Receiver operator characteristic (ROC) curve was used to compare the diagnostic performance of C-TIRADS

CEUS and a combination of both methods. Results ROC curve showed that AUC of C-TIRADS

CEUS and the combination of both methods were 0.820

0.824 and 0.886 respectively. The optimal truncation values in differentiating benign and malignant nodules were 4C

2points and 4C. The area under the ROC of CEUS combined with C-TIRADS classification was higher than those of C-TIRADS classification and CEUS scoring

the difference was statistically significant (Z=3.183，P<0.01；Z=2.070，P=0.038)．Conclusion CEUS has revised value for C-TIRADS 4 nodules. CEUS combined with C-TIRADS classification can significantly improve the diagnostic performance of benign and malignant thyroid nodules.

关键词

甲状腺结节超声造影甲状腺影像学报告及数据系统鉴别诊断

Keywords

Thyroid noduleContrast-enhanced ultrasoundthyroid imaging report and data systemDifferential diagnosis

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