Objective: To evaluate the effect of ultrasound-guided thoracic paravertebral nerve block anesthesia on cognitive function in elderly patients with lung cancer undergoing thoracotomy.Methods:80 elderly patients with lung cancer treated in our hospital from January 2015 to December 2018 were divided into two groups

before anesthesia

the observation group (n=40) received ultrasound-guided paravertebral nerve block

while the control group (n=50) received epidural block

hemodynamic changes

postoperative pain and cognitive function were observed.Results:At the time points of T2-T5

MAP and HR in the observation group were significantly lower than those in the control group(P＜0.05)

there was no significant difference in MAP and HR at T1 between the two groups(P＞0.05);After withdrawal

the average time for patients in the observation group to resume spontaneous breathing

swallowing and breathing was significantly shorter than that in the control group(P＜0.05);There was no significant difference in VAS score between the two groups at 6

12

24 and 48 hours after operation(P＞0.05);There was no significant difference in MMSE score between the two groups before and 48 hours after operation(P＞0.05)

at 1h

6h and 24h after operation

the MMSE score of observation group was significantly higher than that of control group(P＜0.05).Conclusion:When patients with lung cancer undergo thoracotomy

uitrasound-guided paravertebral nerve block was used

can keep the hemodynamics of patients in good stability

and the analgesic effect is ideal

and it will not have a significant impact on the cognitive function of patients after operation.