Objective: To explore the value of color Doppler ultrasound combined with VTIQ in evaluating the mobility of the wrist synovial membrane in rheumatoid arthritis. Methods: Sixty-four RA patients (64 wrist joints in total) were selected as the research objects

and they were divided into active group and remission group based on DAS28 score. CDFI and VTIQ were performed on the wrist joints of the two groups of patients

and the CDFI blood flow classification and SWV parameters (SWVmax

SWVmin

SWVmeanSWVstd) were obtained

and the differences between the two groups were compared. Draw the ROC curve of the synovial membrane

and compare the diagnostic efficiency of each parameter of SWV on the activity of the synovial membrane with AUC. Kappa test was used to compare the evaluation value of CDFI

VTIQ and the combination of the two on synovial activity. Results: Among the 64 wrist synoviums

there were 35 in the active group and 29 in the remission group. The CDFI blood flow classification and SWV parameters of the wrist in the active group were higher than those in the remission group

and the difference was statistically significant (P<0.05). ROC curve analysis found that SWVmean has the best diagnostic performance for evaluating synovial activity among the various parameters of SWV. When the cut-off value is 4.140m/s

SWVmean has the sensitivity

specificity

accuracy

positive predictive value and positive predictive value for diagnosing synovial activity. The negative predictive values ??were 74.28%

89.29%

79.68%

89.65% and 73.52%

respectively. CDFI

VTIQ and the combination of the two have good consistency in synovial activity evaluation (Kappa values ??are 0.561

0.628 and 0.718 respectively)

and the combined application of the two has significantly higher diagnostic sensitivity

accuracy

negative predictive value and Kappa value In a single method (P<0.05). Conclusion: Both CDFI and VTIQ can be used to assess synovial activity in rheumatoid arthritis

and the combined application of the two has a higher diagnostic value.