Clinical analysis of 9 cases of neck Castleman's disease in children

Suo Fengtao

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Clinical analysis of 9 cases of neck Castleman's disease in children

更新时间：2023-04-16

- Clinical analysis of 9 cases of neck Castleman's disease in children
- Journal of Chongqing Medical University Vol. 47, Issue 9, Pages: 1095-1099(2022)
- 作者机构：
  
  重庆医科大学附属儿童医院耳鼻咽喉-头颈外科、儿童发育疾病研究教育部重点实验室、国家儿童健康与疾病临床医学研究中心、儿童发育重大疾病国家国际科技合作基地、儿科学重庆市重点实验室,重庆,400014
- 作者简介：
- 基金信息：
- DOI：
  CLC： R739.91
- Published：2022，
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Suo Fengtao. Clinical analysis of 9 cases of neck Castleman's disease in children. [J]. Journal of Chongqing Medical University 47(9):1095-1099(2022)
DOI：

Suo Fengtao. Clinical analysis of 9 cases of neck Castleman's disease in children. [J]. Journal of Chongqing Medical University 47(9):1095-1099(2022) DOI：

摘要

目的：本文探讨儿童颈部Castleman病（Castleman’s diease，CD）的临床特性，并总结其临床症状、分型、影像学特点、治疗及预后情况。方法：回顾性分析重庆医科大学附属儿童医院2015年8月至2021年7月收治的9例儿童颈部CD的临床资料。结果： 9例患儿中单侧8例，双侧1例，8例以颈部无痛性肿块为主要表现，1例为打鼾，均为单中心型。病理分型均为透明血管型。治疗均行手术切除肿块，术后随访6~60个月，8例一次手术成功，1例复发后行二次手术。结论：儿童颈部CD病主要以无痛性肿块为主要表现，临床分型以单中心（unicentric CD，UCD）为主。影像学检查是重要的术前辅助，但需病理学检查确诊。手术切除是最有效的治疗方法。

Abstract

Objective: To investigate the clinical characteristics of cervical Castleman' s disease (CD) in children and summarize its clinical symptoms

classification

imaging characteristics

treatment and prognosis. Methods: The clinical data of 9 cases of CD in children's neck from August 2015 to July 2021 in Children's Hospital of Chongqing Medical University were retrospectively analyzed. Results: Among the 9 cases

8 cases were unilateral and 1 case was bilateral

with 8 cases of painless mass in the neck and 1 case of snoring as the main manifestation

all of which were single-center type. The pathological types were all hyaline-vascular type. Surgical resection of the mass was performed in all the treatments

and the patients were followed up for 6–60 months after operation. Eight cases were successfully operated once

and another one underwent a second operation after recurrence. Conclusion: Children's neck CD disease is mainly characterized by painless mass

and unicentric CD is the main clinical classification. Imaging assessment is an important pre-operative adjunct

but confirmation of diagnosis still needs histopathological analysis. Surgical resection is the most effective treatment.

关键词

颈部包块Castleman病诊断治疗预后

Keywords

neck massCastleman’s dieasediagnosistreatmentprognosis

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Related Institution

Department of Traditional Chinese Medicine，Children’s Hospital，Zhejiang University School of Medicine/ National Clinical Research Center for Child Health

Department of Pediatrics，The Affiliated Hospital of Nanjing University of Chinese Medicine，The First Clinical Medical College of Nanjing University of Chinese Medicine

Department of Respiratory Medicine，Children’s Hospital，Zhejiang University School of Medicine/ National Clinical Research Center for Child Health

Department of Urology，The Second Affiliated Hospital of Chongqing Medical University, The Second Affiliated Hospital of Chongqing Medical University

Department of Anesthesiology, The Second Affiliated Hospital of Chongqing Medical University

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