Objective: To compare the clinical efficacy of intelligent pressure controlled negative pressure suction flexible ureteroscopic lithotripsy and ordinary flexible ureteroscopic lithotripsy in the treatment of renal cast stones. Methods: The clinical data of 64 patients with renal cast stones who underwent flexible ureteroscopic lithotripsy in The First Affiliated Hospital of Chongqing Medical University and Ganzhou People's Hospital from September 2017 to August 2021 were analyzed retrospectively. There were 42 males and 22 females

with an average age of 50.9 years. Among them

41 cases underwent intelligent pressure controlled negative pressure suction flexible ureteroscopic lithotripsy (pressure controlled group)

and 23 cases underwent ordinary electronic flexible ureteroscopic lithotripsy (non-pressure controlled group). The t test

Chi-square test or Fisher's exact test were used to compare the free stone rate

incidence of complications

postoperative white blood cells

operation time

hospital stay and total hospitalization cost between the two groups. Results: The operation time in the pressure controlled group was longer than that in the non-pressure controlled group [ (78.9±29.8) min vs. (60.7±32.1) min

t=2.278

P=0.026]

the free stone rate was higher than that in the non-pressure controlled group (73.1% vs. 0%

χ2=28.808

P=0.000)

and the total hospitalization cost was lower than that of the non-pressure controlled group [ (24 215.9±3 848.8) vs. (26 497.9±4 230.2)

t=2.196

P=0.032]. There was no significant difference between the two groups in the incidence of complications (19.5% vs. 17.3%

χ2=0.044

P=0.835)

the length of hospital stay [ (8.22±2.94) d vs. (6.87±1.79) d

t=1.997

P=0.05] and postoperative white blood cells [ (9.83±5.72) ×109/L vs. (9.06±2.49) ×109/L

t=0.067

P=0.546]. Conclusion: For renal cast stones

intelligent pressure controlled negative pressure suction flexible ureteroscopic lithotripsy has higher free stone rate

less total hospitalization cost and higher benefit for patients than ordinary electronic flexible ureteroscopic lithotripsy.