Objective: To explore the best placement time and effect evaluation of dinoprostone suppository for full-term pregnancy induction with different Bishop’s cervical scores. Methods: Full-term pregnant women were divided into ≤3 groups

4 groups and 5 groups according to Bishop’s cervical score. According to the placement time of dinoprostone suppository

each score group was divided into morning group (08:00-12:59)

afternoon group (13:00-17:59) and evening group (18:00-22:59)

and the effective rates of cervical ripening

stages of labor and pregnancy outcomes of all groups were retrospectively analyzed. Results: A total of 1 139 pregnant women were enrolled

and the effective rate of cervical ripening was 93.59%. The effective rates of cervical ripening were 95.75%

92.93% and 90.12% in each group with cervical score ≤3

4 and 5 points before induction of labor (P<0.05). In the effective group

the incidence of amniotic fluid fecal contamination was 11.07%

fetal distress was 1.13%

and postpartum hemorrhage was 2.16%. Among the vaginal delivery women

when the Bishop score of cervix was less than or equal to 3

the primipara’s time from delivery to vaginal delivery was the shortest (4.82 h

P=0.005). The time from parturient to vaginal delivery was also the shortest (4.01 h

P=0.044). There was no significant difference in other indexes between groups. Conclusion: Dinoprostolone suppository is safe and effective for induction of labor in full-term pregnancy. For pregnant women with cervical score≤3

dinoprostone suppository can be placed at night to induce labor. For those with cervical score > 3

it can be placed at a time when medical staff are energetic

convenient to operate and can observe closely.