Objective: To investigate the clinical therapeutic effect of spleen-preserving surgery for traumatic spleen rupture based on radiofrequency ablation (RFA) and autologous blood transfusion (ABT)

and to improve the treatment of traumatic splenic rupture in primary hospitals. Methods: Data of 98 cases with traumatic splenic rupture treated in our hospital from January 2015 to May 2020 were retrospectively analyzed

among which

37 cases underwent splenectomy (group A)

14 cases underwent traditional spleen-preserving operation (group B) and 47 cases underwent RFA-assisted spleen-preserving operation (group C). The operation effect

complications and postoperative blood platelet (PLT) count of the three groups were compared and analyzed. Results: The success rate of spleen-preserving surgery in group C was higher than that in group B (P=0.035). There were significant differences among the three groups in operation time (F=20.432

P=0.000). Comparison between groups: the operation time of group C and group A were shorter than that of group B (P=0.000

0.000)

as well as group A had shorter time than group B had (P=0.008). There were significant differences in intraoperative bleeding among the three groups (F=5.462

P=0.006). Comparison between groups: group C and group A had less bleeding than group B had (P=0.010

0.001)

while there was no significant difference between group A and group C (P=0.311). ABT ratio: the differences among the three groups were statistically significant (χ2=7.607

P=0.028); comparison between groups: group C was higher than group A (P=0.012)

while there was no significant difference between group A and group B (P=1.000)

neither in group B and group C (P=0.124). There were no significant differences among the three groups in postoperative hemoglobin (HB) (F=2.864

P=0.062). The differences in hospitalization time among the three groups were statistically significant (F=3.806

P=0.028); comparison between groups: the hospitalization in group C was shorter than that in group A (P=0.010)

while there was no significant difference between group A and group B (P=0.100)

neither in group B and group C (P=0.708). Postoperative complications: the incidence in group C was lower than that in group A and group B

without statistical differences (χ2=1.180

P=0.532). PLT was respectively checked for three groups of patients on the 3rd

7th

15th and 1st month after the operation

and the results showed that the differences among the three groups were statistically significant (F=8.550

4.261

4.304

11.505

P=0.000

0.017

0.016

0.000); comparison between groups: the level of PLT elevation were lower in group C and group B than in group A (P=0.000

0.007

0.008

0.000; 0.004

0.047

0.038

0.001)

while there was no significant difference between group B and group C (P=0.815

0.929

0.837

0.932). Conclusion: RFA combined with intraoperative ABT is a safe and effective method for spleen-preserving operation in traumatic splenic rupture

with high success rate

shortened operation time

reduced intraoperative bleeding

and decreased degree of PLT elevation

which is suitable for promotion in primary hospitals.