Objective To analyze the correlation of carotid intimamedia thickness (CIMT) and plaque

and to predict the significance of coronary artery disease.Methods Angiography and carotid ultrasound results of 100 consecutive outpatients from October 2017 to August 2018 in Bishan people′s hospital were discussed.The extent of coronary stenosis was determined by using an angiographic scoring method and comparatively analyzed with the carotid intimamedia thickness

maximum plaque height and total plaque area in the bulbs by ultrasound measurement.Cutoff values of different parameters

which were achieved based on the receiver operating characteristic curves

were used to analyze the significance of coronary artery disease.Results For the cases with stenosis≥50%

the carotid intimamedia thickness

maximum plaque height

and total plaque area were (0.92±0.05) mm

(2.59±0.70) mm

and (45.3±12.0) mm2

respectively.They were significantly higher than those of stenosis <50% with (0.79±0.06) mm

(1.67±0.69)mm

(30.8±12.8) mm2

respectively.Which indicated that the increase of CIMT

as well as plaque height and area correlated with the significance of coronary artery disease(P<0.01).The optimal threshold values for coronary disease prediction were 0.83 mm

1.55 mm

28.5 mm2 for carotid intimamedia thickness

plaque height

and total plaque area

respectively.In these indicators

CIMT had the best negative likelihood ratio (0.07) for ruling out disease.ConclusionMeasurements of the carotid intimamedia thickness and plaque are of important significance for predicting coronary artery stenosis and coronary artery disease.Besides the commonused CIMT

plaque morphology can be also used as a sensitive imaging biomarker to determine the significance of coronary artery disease.