Objective At present

the mainstream surgical mode and the gold standard for the treatment of spine related diseases are still the intervertebral fusion with the intervertebral implantation of the intervertebral fusion device.The intervertebral fusion device routinely used in clinical practice cannot degrade in vivo after implantation

resulting in lifelong foreign body. High elastic modulus also leads to osteoporosis in adjacent vertebral bodies

which leads to implant sinking

stress shielding and ‘pseudomorphism’ of fusion.The ideal biodegradable synthetic intervertebral fusion cage can be progressively degraded and eventually replaced by new bone，which has the advantages of elastic modulus close to cortical bone

good biocompatibility

X-ray permeability and good initial mechanical strength. In this paper

animal analysis of biodegradable intervertebral fusion cage

clinical effect analysis

current shortcomings and future trends were reviewed.