OBJECTIVE:To establish a method for the contents determination of microelements in Chrysanthemum indicum from different production fields. METHODS:Graphite furnace atomic absorption (GFAAS) was used to determine the contents of Pb, Cd and As; HGAAS was used to determination the content of Hg; and FAAS was used to determine the contents of Cu, Fe, Mn, Ca, Mg and Zn. RESULTS: The linear range was 0-50 μg/L for Pb(r=0.999 9), 0-10 μg/L for Cd(r=0.999 2),0-50 μg/L for As (r=0.999 0),0-20 μg/L for Hg(r=0.999 5),0-5 μg/L for Cu(r=0.999 3), 0-15 μg/L for Fe(r=0.999 8),0-2 μg/L for Mn(r=0.999 9),0-50 μg/L for Ca(r=1.000 0),0-20 μg/L for Mg(r=0.999 9) and 0-2 μg/L for Zn(r=0.999 8); RSDs of precision, stability and reroducibility tests were lower than 3%; recoveries were 94.25%~97.43%(RSD=1.07%)、94.97%~99.46%(RSD=1.68%)、96.25%~99.46%(RSD=1.09%,n=6)、96.61%~99.91%(RSD=1.26%,n=6)、94.11%~98.41%(RSD=1.68%,n=6)、93.11%~99.59%(RSD=2.73%,n=6)、93.11%~99.48%(RSD=2.63%,n=6)、93.01%~99.85%(RSD=2.49%,n=6)、95.13%~99.75%(RSD=1.58%,n=6)、94.08%~97.37%(RSD=1.18%,n=6), respectively. CONCLUSIONS:The method is simple, stable and reproducible, and can be used for the contents determination of microelements in C. indicum from different production fields.