OBJECTIVE:To explore the feasibility and significance of scenario-experiential teaching combined with problem- based learning (PBL) in orthopedic clinical internship to improve the quality of orthopedic clinical internship. METHODS: 135 orthopedics undergraduate trainees were randomly divided into observation group(n=64) and control group(n=71). Observationgroup was trained byscenario-experiential combined with PBL, while the control group was educated by the conventional method.The teaching effect were compared by questionnaire and assessment between the 2 groups. RESULTS: The students in the observationgroup got significantly higher examination scores in satisfaction of teaching methods and teachers, pleasure degree in classroom, mastery of knowledge comprehension, orthopedics theory test, practical operation, specialist examination and case analysis than those incontrol group, the difference was statistically significant(P<0.05). CONCLUSIONS: The new teaching pattern can arouse students’ initiative interesting, improve students’ comprehensive ability and the quality of orthopedic internship.