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SUN Xiaolin; SONG Zhan; LIU Yanjuan; QIAN Guowu

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更新时间：2023-03-01

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- China Pharmacy Vol. 27, Issue 17, (2016)
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SUN Xiaolin, SONG Zhan, LIU Yanjuan, et al. [J]. China Pharmacy 27(17).(2016)
DOI：

SUN Xiaolin, SONG Zhan, LIU Yanjuan, et al. [J]. China Pharmacy 27(17).(2016) DOI：

摘要

目的：探讨生大黄脐疗联合早期结肠灌洗对高龄结肠造口患者生存质量的影响。方法：80例腹会阴联合直肠癌根治术患者按随机数字表法分为对照组和观察组，各40例。对照组患者给予早期结肠灌洗；观察组患者在对照组基础上加用生大黄脐疗。两组疗程均为1个月，疗程结束后均随访6个月。采用癌症患者生存质量量表（QLQ-C30）评估两组患者治疗前后的生存质量，并计算治疗前后的治疗费用。结果：与治疗前比较，两组患者治疗后1、3、6个月的各项功能评分及总体健康状况评分均显著提高，各项症状评分及单一条目评分均显著降低，差异均有统计学意义（P＜0.05）。治疗后1、3、6个月，观察组患者的角色功能、社会功能、认知功能、情绪功能及总体健康状况评分均明显高于对照组，失眠、疼痛评分均明显低于对照组，差异均有统计学意义（P＜0.05）。治疗后3、6个月，观察组患者的腹泻和经济困难评分均明显低于对照组；治疗后1个月，观察组患者的食欲丧失评分明显低于对照组；治疗后6个月，观察组患者的疲倦、恶心与呕吐评分均明显低于对照组，差异均有统计学意义（P＜0.05）。治疗后6个月，观察组患者的护理费用、产品费用及总费用均明显低于对照组，差异均有统计学意义（P＜0.05）。结论：生大黄脐疗联合早期结肠灌洗能明显提高高龄结肠造口患者的生存质量，减少治疗费用。

Abstract

OBJECTIVE： To explore the effects of umbilical therapy by Rheum plamatum combined with early colonic irrigation on the quality of life in elderly patients with colon stoma. METHODS： 80 patients underwent radical resection of abdominoperineal rectal carcinoma were randomly divided into control group and observation， with 40 cases in each group. Control group was given early colonic irrigation； observation group was additionally given umbilical therapy by R. plamatum. Treatment course of 2 groups lasted for one month， and both were followed up for 6 months after treatment. The quality by life in 2 groups was evaluated by using QLQ-C30， and therapy costs were calculated before and after treatment. RESULTS： Compared with before treatment， function score and total health score of 2 groups improved significantly in 1， 3， 6 months after treatment， while symptom score and single item score decreased significantly， with statistical significance （P＜0.05）. In 1， 3， 6 months after treatment， role function， social function， cognitive function， emotional function and total health score of observation group were significantly higher than those of control group， and insomnia and pain score were significantly lower than control group， with statistical significance （P＜0.05）. 3 and 6 months after treatment， diarrhea and economic difficulty score of observation group were significantly lower than those of control group， with statistical significance （P＜0.05）. 1 months after treatment， loss of appetite score of observation group were significantly lower than those of control group， with statistical significance （P＜0.05）. 6 months after treatment， ?fatigue， nausea and vomiting score of observation group were significantly lower than those of control group， with statistical significance （P＜0.05）. 6 months after treatment， nursing cost， drug cost and total cost of observation group were significantly lower than those of control group， with statistical significance （P＜0.05）. CONCLUSIONS： The umbilical therapy by R. plamatum combined with early colonic irrigation can improve the quality of life in elderly patients with colon stoma significantly and reduce treatment cost.

关键词

生大黄脐疗腹会阴联合直肠癌根治术结肠造口生存质量高龄

Keywords

Rheum plamatumUmbilical therapyRadical resection of abdominoperineal rectal carcinomaColon stomaQuality of lifeElderly

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