OBJECTIVE： To provide reference for improving the internship teaching for pharmacy students. METHODS： Self-made questionnaire was adopted to investigate the shared learning attitude and self-confidence of pharmacy students in our hospital before and after small group teaching from Aug. 2012 to Aug. 2014； knowledge and skills assessment was conducted for the students. RESULTS： 72 questionnaires were respectively sent out before and after small group teaching， 72 were respectively received with effective recovery of 100％. There were significant differences for the undergraduates and specialists in improving their future working relationships， understanding of anesthetic prescription knowledge and management capacity， supplementing the lack knowledge caused by curriculum differences， enhancing the ability to communicate with patients， dispensing prescription of narcotic drugs for patients， preferring accepting other medical staff consulting narcotic drugs-related problems， more confident to deal prescription of narcotic drugs with physicians， improving their pharmacy practice skills， knowledge and skill assessment before and after small group teaching （P＜0.05）， no significant differences in ultimately benefit to patients （P＞0.05）； while there was no significant difference for the specialists in helping the students understanding their major’s limits before and after small group teaching（P＞0.05），the undergraduates were the opposite； there was no significant diffecrence for the undergraduates in terms of it is conducive to cultivating team spirit and ensuring the responsibility in prescription and the safety and management of narcotic drugs before and after small group（P＞0.05），the specialists were the opposite. CONCLUSIONS： Small group teaching is conducive to sharing learning， enhancing self-confidence and professional knowledge and skills for pharmacy students.