OBJECTIVE： To investigate the influence of sevoflurane inhalation anesthesia and propofol intravenous anesthesia on hemodynamics， stress reaction and anesthesia effects of pediatric hernia surgery. METHODS： Eight-six children underwent hernia surgery in Hubei Provincial Third People’s Hospital from May 2011 to Sept. 2015 were selected as subjects and divided into trial group and control group according to random number table， with 43 cases in each group. Trial group was given Tirofiban hydrochloride for injection 0.4 μg/（kg·min），ivgtt， Cisatracurium besilate for injection 0.1 mg/kg+Fentanyl citrate injection 1.0 μg/kg，iv， for anesthesia induction； given 2％-3％ sevoflurane inhalation for anesthesia maintenance， and additionally given fentanyl citrate 0.5 μg/kg， iv if necessary. Control group was given Propofol emulsion injection 3 mg/kg+atracurium 0.1 mg/kg+ fentanyl citrate 1.0 μg/kg， iv for anesthesia induction； given micro pump injection of propofol 3 mg/（kg·h）for anesthesia maintenance， and additionally given fentanyl citrate 0.5 μg/kg，iv if necessary. The onset time of anesthesia， hemodynamic parameters （SBP， DBP， HR）， stress reaction indexes （NE， E， R）， recovery situation and the occurrence of ADR were observed in 2 groups. RESULTS： The onset time of anesthesia in trial group was （3.82±0.45） min， significantly shorter than control group （5.13±0.74） min， with statistical significance （P＜0.05）. Before anesthesia induction， there was no statistical significance in SBP， DBP， HR， the serum levels of NE， E and R between 2 groups （P＞0.05）. The levels of SBP， DBP， HR of 2 groups at incision， 5 min after incision， 10 min after incision were significantly higher than before anesthesia， with statistical significance （P＜0.05）. Above indexes of trial group at incision， 5 min after incision were significantly lower than control group， with statistical significance （P＜0.05）. At incision， the serum levels of NE， E and R in 2 groups were increased significantly compared to before anesthesia induction， but the trial group was significantly lower than the control group， with statistical significance （P＜0.05）. The postoperative eye opening time， awake time and orientation recovery time of trial group were significantly shorter than control group， while the PAED score was significantly lower than control group， with statistical significance （P＜0.05）. The incidence of ADR in trial group （0） was significantly lower than control group （11.6％）， with statistical significance （P＜0.05）. CONCLUSIONS： Sevoflurane inhalation anesthesia has less effect than propofol intravenous anesthesia on hemodynamic indexes and is helpful to relieve stress reaction and promote postoperative revival with good safety.