OBJECTIVE： To provide reference for improving pharmaceutical care in the construction of medical union. METHODS： Based on the work practice of the author， the status of the pharmaceutical care in the construction of medical union was analyzed， and the reasonable suggestions were put forward from the aspects of clinical pathway， drug purchasing， information construction， pharmacist training and residents’awareness of durg use， etc. RESULTS： There were some problems in pharmaceutical care of medical union， such as the level of knowledge and guidance ability in pharmaceutical staff were different； catalogue of drugs supplied by medical institutions of different levels were inconsistent； patient information could not be shared and exchanged； prescription automatic screening system was seriously inadequate. In view of these problems， it was suggested to solve these problems in five aspects， such as implementing clinical pathway， promoting standard disease diagnosis and treatment； realizing unified procurement of drugs in medical union， guaranteeing homogenization of drug supply； establishing information platform for medical union， realizing information integration； establishing pharmaceutical alliance in medical union， updating pharmaceutical knowledge； building WeChat public service platform， improving awareness of medication safety among residents. CONCLUSIONS： With the rapid development of social economy and the continuous reform of the medical system， the demand for medical quality and pharmaceutical service has gradually improved. The capacity improvement of pharmaceutical care can help promote the development of medical union， and ensure that residents receive equal， homogenized and integrated health care services.