OBJECTIVE: To observe clinical efficacy and safety of Modified yupingfeng powder decoction in the treatment of elderly patients with type 2 diabetes hyperhidrosis. METHODS: A total of 120 elderly patients with type 2 diabetes hyperhidrosis selected from outpatient of our hospital during Jan. 2015 to Jun. 2016 were divided into control group and observation group according to random number table, with 60 cases in each group. Control group was given routine chemical drug therapy of diabetes. Observation group was additionally given Modified yupingfeng powder, decocted with water, 300 mL each time, 150 mL morning and night, 1 h before meal, on the basis of control group. Treatment courses of 2 groups both were 1 month. Blood glucose indexes (FPG, 2 hPG, HbA1c) and TCM symptom scores before and after treatment were compared between 2 groups. Clinical efficacies and the occurrence of ADR were observed. RESULTS: Before treatment, there was no statistical significance in FPG, 2 hPG, HbA1c or TCM symptom scores between 2 groups (P>0.05). Compared to before treatment, FPG,2 hPG, HbA1c and TCM symptom scores of 2 groups were decreased significantly after treatment; the levels of FPG, HbA1c and TCM symptom score in observation group were significantly lower than control group, with statistical significance (P<0.05). But there was no statistical significance in 2 hPG between 2 groups (P>0.05). Total response rate of observation group (90.00%) was significantly higher than that of control group (70.00%), with statistical significance (P<0.05). No obvious ADR was found in 2 groups. CONCLUSIONS: Modified yupingfeng powder decoction can effectively improve the clinical symptoms, and shows good therapeutic efficacy and safety for elderly patients with type 2 diabetes hyperhidrosis.
关键词
2型糖尿病糖尿病多汗症老年患者加味玉屏风散中医症状
Keywords
Type 2 diabetesDiabetes hyperhidrosisElderly patientsModified yupingfeng powderTCM symptoms