Objective To investigate the effect of imagination training in combination with occupational therapy on physical function and quality of life in patients with stroke hemiplegia. Methods A total of 76 patients with stroke hemiplegia admitted to a hospital in Zhengzhou from June 2018 to June 2019 were selected and randomly assigned to a control group and an observation group

with 38 cases in each group. The patients in the control group and in the observation group received occupational therapy and imagination training（in addition to nursing care in the control group）

respectively. Patients in both groups received continuous intervention for 3 months. The clinical efficacy was compared between the two groups

and the National Institutes of Health Stroke Scale（NIHSS） score

Fugl-Meyer Motor Function Scale score

Activities of Daily Living Scale（ADL） score

Berg Balance Scale score

Stroke Specific Quality of Life Scale（SS-QOL） score

thromboxane A

2

（TXA

2

） and prostaglandin I

2

（PGI

2

） levels were compared between the two groups before and after the intervention.Results Total effective rate of clinical efficacy in the observation group was 92.11%

which was significantly higher than that of the control group（71.05%）（P

<

0.05）.After the intervention

the NIHSS score and serum TXA

2

levels in the two groups were lower than those before the intervention

and the observation group was lower than the control group

with statistically significant differences（P

<

0.05）.After the intervention

the Fugl-Meyer

ADL

Berg

SS-QOL scores and serum PGI

2

levels in the two groups were higher than those before the intervention

and the observation group was higher than the control group

with statistically significant differences（P

<

0.05）.Conclusion Imagination training in combination with occupational therapy can effectively reduce the degree of neurological deficits

improve limb motor function

balance ability

and activities of daily living

and improve the quality of life in stroke patients with hemiplegia. These benefits justify a wider application of this procedure in clinical practice.