Objective To investigate the efficacy of a modified circumareolar radical mastectomy with nipple-areola complex preservation for early-stage breast cancer.Methods Ninety cases of early-stage breast cancer patients admitted to a hospital in Henan Province from May 2017 to April 2019 were enrolled for this study.A random number table was used to divide the patients into observation group and control group

45 cases each.Patients in the control group were given conventional radical mastectomy for breast cancer

and patients in the observation group were given modified circumareolar radical mastectomy with nipple-areola complex preservation.The quality of life at the time of discharge was assessed according to the Functiond Assessment of Cancer Therapy-Breast（FACT-B） developed by the Chicago Medical Center

USA.Local recurrence

distant metastasis and survival were compared between the 2 groups of patients at 2 years of hospital discharge.The occurrence of complications from postoperative period to hospital discharge was compared between the 2 groups of patients.Results Preoperative FACT-B scores of patients in the 2 groups were compared

and the difference was not statistically significant（P<0.05）.At the time of discharge

the scores of psychological

social

spiritual and somatic dimensions in the FACT-B of patients in the observation group were 114.32±37.41

50.02±19.45

41.51±13.66 and 57.78±17.96

respectively

which were higher than those of the control group at 98.62±32.89

40.32±17.22

31.45±11.13 and 50.34±15.56

with statistically significant differences（P<0.05）.There was no statistically significant difference between the local recurrence rate

distant metastasis rate and survival rate of the 2 groups（P>0.05）.The complication rate of patients in the observation group was 6.66%

which was lower than that of 22.20% in the control group

and the difference was statistically significant（P<0.05）.Conclusion The modified circumareolar radical mastectomy with nipple-areola complex preservation has good efficacy in the treatment of breast cancer

which can improve the survival quality of patients and reduce the incidence of postoperative complications

and is a safe

effective and scientific treatment method that is worthy of wider clinical practice.