Analysis of factors affecting serum 25-hydroxyvitamin D<sub>3</sub> levels in children with infectious diarrhea

Xing Hanye; Chen Yun; Wang Jin

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Analysis of factors affecting serum 25-hydroxyvitamin D₃ levels in children with infectious diarrhea

更新时间：2022-11-04

- Analysis of factors affecting serum 25-hydroxyvitamin D₃ levels in children with infectious diarrhea
- Health Medicine Research and Practice Vol. 19, Issue 4, Pages: 63-66(2022)
- 作者机构：
  
  南阳医学高等专科学校第一附属医院儿科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R725.7
- Published：2022，
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Xing Hanye, Chen Yun, Wang Jin. Analysis of factors affecting serum 25-hydroxyvitamin D₃ levels in children with infectious diarrhea. [J]. Health Medicine Research and Practice 19(4):63-66(2022)
DOI：

Xing Hanye, Chen Yun, Wang Jin. Analysis of factors affecting serum 25-hydroxyvitamin D₃ levels in children with infectious diarrhea. [J]. Health Medicine Research and Practice 19(4):63-66(2022) DOI：

摘要

目的探讨感染性腹泻患儿血清25-羟维生素D

[25-（OH）D

]水平的影响因素。方法选取南阳市某医院2019年2月—2021年2月收治的80例感染性腹泻患儿为观察组

选取同期医院招募的40例健康儿童志愿者为对照组。比较2组儿童血清25-（OH）D

水平

分析影响感染性腹泻患儿血清25-（OH）D

水平的危险因素。结果本研究纳入血清25-（OH）D

水平正常感染性腹泻患儿40例

血清25-（OH）D

水平下降感染性腹泻患儿40例。观察组儿童血清25-（OH）D

水平为（31.26±5.33）μg/L

低于对照组的（38.01±6.54）μg/L

差异有统计学意义（t=6.054

0.001）。多因素logistic回归分析结果显示

乱服或未服维生素D制剂、单独母乳喂养、母亲文化程度低、反复上呼吸道感染、反复腹泻发作、反复支气管哮喘发作为感染性腹泻患儿血清25-（OH）D

水平下降的危险因素。结论 25-（OH）D

缺乏是儿童感染性腹泻发病的重要原因之一

影响感染性腹泻患儿血清25-（OH）D

水平的危险因素较多

对危险因素进行积极干预可显著改善患儿病情。

Abstract

Objective To investigate the factors influencing 25-hydroxyvitamin D

[25-（OH）D

] levels in the serum of children with infectious diarrhea. Methods Eighty cases of children with infectious diarrhea admitted to a hospital in Nanyang from February 2019 to February 2021 were selected as the observation group

and 40 healthy child volunteers recruited from the hospital during the same period were selected as the control group. The serum 25-（OH）D

levels of children in the 2 groups were compared

and the risk factors affecting serum 25-（OH）D

levels were analyzed. Results Forty children with infectious diarrhea with normal serum 25-（OH）D3 levels and 40 children with infectious diarrhea with deficient serum 25-（OH）D

levels were included in this study. The serum 25-（OH）D

level of children in the observation group was 31.26±5.33 μg/L

which was lower than that of the control group（38.01±6.54 μg/L）

and the difference was statistically significant（t=6.054

0.001）. The results of multifactorial logistic regression analysis showed that not taking vitamin D preparations or taking them indiscriminately

breastfeeding alone

low maternal literacy

recurrent upper respiratory tract infections

recurrent diarrheal disease

and recurrent bronchial asthma were risk factors affecting serum 25-（OH）D

levels in children with infectious diarrhea. Conclusion 25-（OH）D

deficiency is one of the important causes of the development of infectious diarrhea in children

and there are many risk factors affecting serum 25-（OH）D

levels in children with infectious diarrhea; active interventions on risk factors can significantly improve the condition of children.

关键词

25-羟维生素D3感染性腹泻儿童预后

Keywords

25-Hydroxyvitamin D3Infectious diarrheachildrenPrognosis

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Analysis of factors affecting serum 25-hydroxyvitamin D3 levels in children with infectious diarrhea

DOI：

摘要

Abstract

关键词

Keywords

references

Analysis of factors affecting serum 25-hydroxyvitamin D₃ levels in children with infectious diarrhea